High-dose-rate <sup>192</sup>Ir brachytherapy combined with external irradiation therapy for cancer  of the uterine cervix

DAI  Xiaobo; et al

doi:10.13406/j.cnki.cyxb.2002.01.029

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High-dose-rate ¹⁹²Ir brachytherapy combined with external irradiation therapy for cancer of the uterine cervix

更新时间：2024-01-17

- High-dose-rate ¹⁹²Ir brachytherapy combined with external irradiation therapy for cancer of the uterine cervix
- Journal of Chongqing Medical University Issue 1, Pages: 86-88(2002)
- 作者机构：
  
  1. 重庆医科大学临床学院放疗科
  2. 重庆医科大学临床学院放疗科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2002.01.029
  CLC： R737.33
- Published：2002，
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[1]戴晓波,陈晓品,张玲.高剂量率~(192)Ir腔内近距离加体外照射治疗宫颈癌[J].重庆医科大学学报,2002(01):86-88.

DAI Xiaobo, et al. High-dose-rate ¹⁹²Ir brachytherapy combined with external irradiation therapy for cancer of the uterine cervix. [J]. Journal of Chongqing Medical University (1):86-88(2002)
[1]戴晓波,陈晓品,张玲.高剂量率~(192)Ir腔内近距离加体外照射治疗宫颈癌[J].重庆医科大学学报,2002(01):86-88. DOI： 10.13406/j.cnki.cyxb.2002.01.029.

DAI Xiaobo, et al. High-dose-rate ¹⁹²Ir brachytherapy combined with external irradiation therapy for cancer of the uterine cervix. [J]. Journal of Chongqing Medical University (1):86-88(2002) DOI： 10.13406/j.cnki.cyxb.2002.01.029.

摘要

目的：回顾分析高剂量率１９２Ｉｒ近距离治疗加体外照射治疗宫颈癌的疗效及生存率。　方法：　１９９３年５月至１９９７年５月，５４例子宫颈癌采用高剂量率１９２Ｉｒ近距离加体外照射治疗，其中Ⅰ期２例，Ⅱ期２９例，Ⅲ期２１例，Ⅳ期２例。体外和腔内照射Ａ点总量为６５～８５Ｇｙ，Ｂ点剂量５０～７０Ｇｙ，治疗时间６～８周。　结果：本组总的１、３、４年生存率８１．５％、６８．５％、６１．１％。Ⅰ、Ⅱ、Ⅲ、Ⅳ期４年生存率分别为１００％、７５．９％、４２．８％和０％，临床分期是决定预后的重要因素。放射性直肠炎及放射性膀胱炎发生率分别是３１．５％和１１．１％。结论：　宫颈癌的腔内与体外放射治疗是其有效的治疗手段，但如何进一步提高治愈率，降低并发症仍是今后研究的方向。

Abstract

Objective: To analyze retrospectively results of cervix carcinoma treated by high dose rate 192Ir intracavitary brachytherapy and external irradiation. Methods: From May 1993 to May 1997，54 cases of cervix carcinoma were treated by combined external radiation with brachytherapy . The patient population consisted of 2 cases with stageⅠ disease

29 cases with stage Ⅱ disease

21 cases with Stage Ⅲ disease and 2 cases with stage Ⅳ disease . The total dose of the external and intracavitary irradiation at point A and B was 65～85Gy and 50～70Gy ，respectively. The total treatment time was 6～8 weeks . Results: The survival rate of 1、3、4 year after radiotherapy was 81.5%，68.5% and 61.1% ，respectively. The 4-year survival for stages Ⅰ、Ⅱ、Ⅲ and Ⅳdisease were 100%、75.8%、42.8% and 0%

respectively .The clinical stage of disease is an important prognostic factor . The incidence of complication was 31.5% for radiation proctitis and 11.1% for cystitis. Conclusion:HDR brachytherapy with external irradiation for the cervix carcinoma is an effective method. To improve tumor control and reduce complication rate more research is necessary.

关键词

宫颈癌近距离治疗体外照射

Keywords

Cervix carcinomaBrachytherapyExternal irradiation

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High-dose-rate 192Ir brachytherapy combined with external irradiation therapy for cancer of the uterine cervix

DOI：10.13406/j.cnki.cyxb.2002.01.029

摘要

Abstract

关键词

Keywords

references

High-dose-rate ¹⁹²Ir brachytherapy combined with external irradiation therapy for cancer of the uterine cervix