The relationship between GH-IGF-I system and IUGR

LIU Bao-qin; et al

doi:10.13406/j.cnki.cyxb.2001.04.005

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The relationship between GH-IGF-I system and IUGR

更新时间：2024-01-17

- The relationship between GH-IGF-I system and IUGR
- Journal of Chongqing Medical University Issue 4, Pages: 375-377(2001)
- 作者机构：
  
  1. 重庆医科大学医学超声工程研究所
  2. 西安交通大学第一临床医学院
  3. 重庆医科大学医学超声工程研究所,重庆,400016
  4. ,西安,710016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2001.04.005
  CLC： R714.51
- Published：2001，
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[1]刘宝琴,吴玲,王智彪,伍烽.生长激素-胰岛素样生长因子-1系统与胎儿宫内发育迟缓的关系[J].重庆医科大学学报,2001(04):375-377+390.

LIU Bao-qin, et al. The relationship between GH-IGF-I system and IUGR. [J]. Journal of Chongqing Medical University (4):375-377(2001)
[1]刘宝琴,吴玲,王智彪,伍烽.生长激素-胰岛素样生长因子-1系统与胎儿宫内发育迟缓的关系[J].重庆医科大学学报,2001(04):375-377+390. DOI： 10.13406/j.cnki.cyxb.2001.04.005.

LIU Bao-qin, et al. The relationship between GH-IGF-I system and IUGR. [J]. Journal of Chongqing Medical University (4):375-377(2001) DOI： 10.13406/j.cnki.cyxb.2001.04.005.

摘要

目的：研究ＧＨ－ＩＧＦ－１系统对特发性ＩＵＧＲ的影响。方法：对１８例足月妊娠合并特发性ＩＵＧＲ及２５例正常足月分娩产妇母血、脐血、羊水、胎盘中的ＩＧＦ－１和ＧＨ进行定量测定。结果：　ＩＵＧＲ组母血、脐血、胎盘组织ＩＧＦ－１、ＧＨ含量明显低于正常对照组，差异有显著性；母血、脐血、胎盘组织ＧＨ含量与各样本中ＩＧＦ－１含量均相关。结论：ＧＨ－ＩＧＦ－１系统在胎儿生长发育中起重要调节作用。

Abstract

Objective: To detect the effects of GH-IGF-I system on the idiopathic IUGR.Methods：18 pregnant women with idiopathic IUGR and 25 normal pregnant women were studied to measure the IGF-I and GH levels of maternal serum

umbilical serum

amniotic fluid and placental tissue. Results： The GH

IGF-I levels of maternal serum

umbilical serum and placental tissue in IUGR group were significantly lower than those in control group. The levels of IGF-I were positively correlated with the levels of GH in every sample.Conclusion:During the development of fetus IGF-I and GH system plays an important regulating role.

关键词

胎儿宫内发育迟缓胰岛素样生长因子-1生长激素胎盘

Keywords

Intrauterine growth retardationInsulin-like growth factor-Igrowth hormoneplacenta

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