Recombinant basic fibrolast growth factor in the treatment of Ⅱ°  acute radiodermatitis

DAI Xiao-bo

doi:10.13406/j.cnki.cyxb.2001.03.040

您当前的位置：

首页 >

文章列表页 >

Recombinant basic fibrolast growth factor in the treatment of Ⅱ° acute radiodermatitis

更新时间：2024-01-17

- Recombinant basic fibrolast growth factor in the treatment of Ⅱ° acute radiodermatitis
- Journal of Chongqing Medical University Issue 3, Pages: 337-339(2001)
- 作者机构：
  
  重庆医科大学临床学院放疗科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2001.03.040
  CLC： R818.7
- Published：2001，
扫描看全文
[1]戴晓波.重组牛碱性成纤维细胞生长因子治疗Ⅱ度急性放射性皮炎[J].重庆医科大学学报,2001(03):337-339.

DAI Xiao-bo. Recombinant basic fibrolast growth factor in the treatment of Ⅱ° acute radiodermatitis. [J]. Journal of Chongqing Medical University (3):337-339(2001)
[1]戴晓波.重组牛碱性成纤维细胞生长因子治疗Ⅱ度急性放射性皮炎[J].重庆医科大学学报,2001(03):337-339. DOI： 10.13406/j.cnki.cyxb.2001.03.040.

DAI Xiao-bo. Recombinant basic fibrolast growth factor in the treatment of Ⅱ° acute radiodermatitis. [J]. Journal of Chongqing Medical University (3):337-339(2001) DOI： 10.13406/j.cnki.cyxb.2001.03.040.

摘要

目的：观察重组牛碱性成纤维细胞生长因子（ｒｂＦＧＦ）治疗Ⅱ度急性放射性皮炎的疗效。方法：４１例放射治疗中发生Ⅱ度急性放射性皮炎的癌症病人，分为治疗组与对照组。治疗组２３例用（ｒｂＦＧＦ）治疗，对照组１８例用常规方法治疗，分别观察两组病人创面愈合时间及毒副反应，分别计算两组资料平均愈合时间及其标准差。应用ｔ检验进行显著性分析。结果：治疗组创面愈合时间４～１４天，平均８．５２±３．２０天，对照组愈合时间７～４０天，平均２１．６１±８．６５天，两组差异有显著性（Ｐ＜０．００１）。结论：ｒｂＦＧＦ治疗Ⅱ度急性放射性皮炎，较常规治疗缩短愈合时间１０天以上，且无任何毒副作用。

Abstract

Objective：To evaluate the efficacy of recom binant basic fibroblast growth factor (rbFGF) in treatment of Ⅱ° acute radiode rmatitis.Methods： 41 patients with Ⅱ° acute radiodermatitis d uring radiotherapy were divided into two groups：23 patients received rbFGF treat ment and 18 patients received conventional treament.Healing time of wounds and toxicity were assessed.All data were shown in ±s

and analyzed with T test.Results：Healing time of wounds were 4～14 days(8.52±3.20)for t he teeatment group

and 7～40 days(21.61±8.65)for the control.There was a statistically significant difference in healing time between the two groups(P＜0.001).Conclusion：rbFGF shortened healing time of wounds o ver 10 days in the treatment of Ⅱ° acute radiodermatitis and had no toxicity.

关键词

重组牛碱性成纤维细胞生长因子急性放射性皮炎

Keywords

Recombinant basic fibroblast growth factorAcute radiodermatitis

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

⁰