Histopathologic examination of uterine smooth muscle tumors

doi:10.13406/j.cnki.cyxb.2000.04.017

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Histopathologic examination of uterine smooth muscle tumors

更新时间：2024-01-17

- Histopathologic examination of uterine smooth muscle tumors
- Journal of Chongqing Medical University Issue 4, Pages: 380-381(2000)
- 作者机构：
  
  重庆医科大学基础医学院病理教研室,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2000.04.017
  CLC： R737.33
- Published：2000，
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[1]宁燕,米粲,李圆圆.子宫平滑肌肿瘤的病理组织学观察[J].重庆医科大学学报,2000(04):380-381+384.

Histopathologic examination of uterine smooth muscle tumors. [J]. Journal of Chongqing Medical University (4):380-381(2000)
[1]宁燕,米粲,李圆圆.子宫平滑肌肿瘤的病理组织学观察[J].重庆医科大学学报,2000(04):380-381+384. DOI： 10.13406/j.cnki.cyxb.2000.04.017.

Histopathologic examination of uterine smooth muscle tumors. [J]. Journal of Chongqing Medical University (4):380-381(2000) DOI： 10.13406/j.cnki.cyxb.2000.04.017.

摘要

目的　探讨子宫平滑肌肿瘤的病理诊断标准及其预后。方法　对病例进行病理组织学观察，并用desmin，actin免疫组织化学染色。结果　多数子宫平滑肌肉瘤核分裂像增多同时伴细胞异型性及凝固性坏死，子宫平滑肌瘤则无以上病理变化。子宫平滑肌肉瘤的desmin和actin阳性细胞显著低于子宫平滑肌瘤。结论　尽管核分裂数是诊断子宫平滑肌肉瘤的重要指标，但不是唯一指标，应综合细胞异型，边界浸润，凝固性坏死这些改变作出诊断，而desmin或（和）actin染色可作为鉴别良恶性子宫平滑肌肿瘤的辅助指标。

Abstract

：Objective To investigate the histological diagnostic criteria and study the prognosis in uterine smooth muscle tumors. Methods Histologic examinations were reviewed and desmin and actin immunohistochemical staining were carried out in 79 uterine smooth muscle tumors. Results In most cases leiomyosarcoma is accompanied by active mitosis

cell atypia and coagulative necrosis

whereas leiomyomas have not shown such changes. Desmin and actin positive cytoplasm stainings were significantly lower in uterine leiomyosarcomas than that in leiomyomas. Conclusion Nuclear mitotic activity is an important but not sole criterion in the diagnosis of uterine leiomyosarcoma; the combination of cellular atypia

margin infiltration

coagulative necrosis should also be taken into consideration. Meantime

desmin or actin staining can be applied as accessary criteria in making a distinction between uterine leiomyosarcoma and leiomyoma.

关键词

子宫平滑肌肉瘤平滑肌瘤免疫组织化学

Keywords

：UterusleiomyosarcomaLeiomyomaimmunohistochemistry

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