Primary study on human papillomavirus type 16 E6,E7 in biopsies of cervical carcinoma and cervicitis

doi:10.13406/j.cnki.cyxb.2000.04.014

您当前的位置：

首页 >

文章列表页 >

Primary study on human papillomavirus type 16 E6,E7 in biopsies of cervical carcinoma and cervicitis

更新时间：2024-01-17

- Primary study on human papillomavirus type 16 E6,E7 in biopsies of cervical carcinoma and cervicitis
- Journal of Chongqing Medical University Issue 4, Pages: 371-372(2000)
- 作者机构：
  
  1. 重庆医科大学第二临床学院妇产科,重庆,400010
  2. 重庆医科大学病毒性肝炎研究所,重庆,400010
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2000.04.014
  CLC： R737.33?
- Published：2000，
扫描看全文
[1]徐波,胡丽娜,顾美礼,任红.16型人乳头状瘤病毒E6、E7与宫颈癌、宫颈炎关系的初步研究[J].重庆医科大学学报,2000(04):371-372+379.

Primary study on human papillomavirus type 16 E6,E7 in biopsies of cervical carcinoma and cervicitis. [J]. Journal of Chongqing Medical University (4):371-372(2000)
[1]徐波,胡丽娜,顾美礼,任红.16型人乳头状瘤病毒E6、E7与宫颈癌、宫颈炎关系的初步研究[J].重庆医科大学学报,2000(04):371-372+379. DOI： 10.13406/j.cnki.cyxb.2000.04.014.

Primary study on human papillomavirus type 16 E6,E7 in biopsies of cervical carcinoma and cervicitis. [J]. Journal of Chongqing Medical University (4):371-372(2000) DOI： 10.13406/j.cnki.cyxb.2000.04.014.

摘要

目的　了解重庆地区宫颈癌、宫颈炎发病与16型人乳头状瘤病毒（HPV16）E6、E7的关系。方法　运用PCR，分子生物学技术进行HPV16 E6、E7的扩增和克隆。结果　重庆地区宫颈癌、宫颈炎组织中HPV16 E6

E7总检出率分别为70%和65%。结论　重庆地区HPV16感染与宫颈癌、宫颈炎的发生相关。E7原癌蛋白可能与宫颈癌发生早期有关，而E6原癌蛋白可能与宫颈癌形成晚期关系密切。

Abstract

：Objective To learn whether HPV16 E6

E7 correlate with cervical carcinoma and cervicitis in Chongqing. Methods Amplification and cloning of HPV16 E6

E7 genes were performed by PCR and molecular biological techniques. Results Detection rates of HPV16 E6

E7 in biopsies of cervical carcinoma and cervicitis were 70% and 65% in Chongqing. Conclusion HPV16 infection might correlate with cervical carcinoma and cervicitis occurrence in Chongqing. E6 might function on advanced stage of cervical carcinoma while E7 might function on early stage .

关键词

16型人乳头状瘤病毒宫颈癌宫颈炎PCR

Keywords

：HPV16cervical carcinomaCervicitisP?

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Expression and clinical significance of BCL11A in human cervical cancer

Comparison between two cervical/vaginal cytologic methods for diagnosing the early cervical diseases

Effect of Hypoxia-inducible factor-1 alpha on the radiosensitivity of rat cervical carcinoma

The relation between local temperature rise and therapeutic effects of focused ultrasound on chronic cervicitis

Comparative analysis of α-tubulin,β-tubulin and γ-tubulin of Immortalized cells and carcinoma cells of the Cervix

Related Author

Song Fangzhou

Liu Geli

Wu Jiayan

Zeng Fan

Li Haiyu

Zhang Hantao

Bai Xin

蒋利华

Related Institution

Molecular Medicine and Tumor Research Center of Chongqing Medical University

Department of Obstetrics and Gynecology,College of Clinical Medicine,Chongqing Medical University

重庆医科大学临床学院妇产科

Department of Radiation Medicine,College of Basic Medicine,Chongqing Medical University

解放军第181医院妇幼中心

⁰