Effect of esmolol on hemodynamics in patients   with general anesthesthesia in extubation

doi:10.13406/j.cnki.cyxb.2000.02.020

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Effect of esmolol on hemodynamics in patients with general anesthesthesia in extubation

更新时间：2024-01-17

- Effect of esmolol on hemodynamics in patients with general anesthesthesia in extubation
- Journal of Chongqing Medical University Issue 2, Pages: 165-166(2000)
- 作者机构：
  
  重庆医科大学第二临床学院麻醉科,400010
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2000.02.020
  CLC： R96
- Published：2000，
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[1]季道如,但伶.艾司洛尔对拔管期血流动力学的影响[J].重庆医科大学学报,2000(02):165-166.

Effect of esmolol on hemodynamics in patients with general anesthesthesia in extubation. [J]. Journal of Chongqing Medical University (2):165-166(2000)
[1]季道如,但伶.艾司洛尔对拔管期血流动力学的影响[J].重庆医科大学学报,2000(02):165-166. DOI： 10.13406/j.cnki.cyxb.2000.02.020.

Effect of esmolol on hemodynamics in patients with general anesthesthesia in extubation. [J]. Journal of Chongqing Medical University (2):165-166(2000) DOI： 10.13406/j.cnki.cyxb.2000.02.020.

摘要

目的 :观察艾司洛尔不同给药方式对拔管期血流动力学的影响。方法 :将 45例ASAI～Ⅱ级择期全麻手术病人随机分成三组（每组 15例）。A组在拔管前 12 .8± 4.5min开始用微量泵持续给予艾司洛尔 2 0 0 μg/kg/min。B组在拔管前2min静注艾司洛尔 1.5mg/kg。C组为对照组。结果 :A、B两组用艾司洛尔后与C组比较HR、SBP、RPP均有明显降低（P <0 .0 5 ）。而B组在停麻药到拔管各指标变化与C组相似（P >0 .0 5 ）。结论 :持续给予艾司洛尔更能有效保持拔管期血流动力学的稳定

Abstract

Objective:To detect the effect of esmolol on hemodynamics in patients with general anesthesia in extubation. Methods:45 patients with general anesthesia were randomly divided into three groups

with 15 cases each. Esmolol was intravenously injected with 200μg/kg/min from 12.8±4.5 min before endotracheal extubation in patients of group A

and only once with 1.5mg/kg at 2 min before endotracheal extubation in patients of groupB. Group C served as control. Results:HR

SBP and RRP were significantly decreased after injecting esmolol in Group A and Group B compared with Group C. However

it is similar in every index in Group B as compared with Group C from stopping injection of drug to extubation. Conclusion:The hemodynamics is more steady with continuous intavenous injection of esmolol than with only one intavenous injection.

关键词

艾司洛尔拔管血流动力学

Keywords

EsmololHemodynamicsExtubation

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