Detection of chlamydia trachomatis from amniotic fluid and   cervical samples at caesarean birth

doi:10.13406/j.cnki.cyxb.2000.02.012

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Detection of chlamydia trachomatis from amniotic fluid and cervical samples at caesarean birth

更新时间：2024-01-17

- Detection of chlamydia trachomatis from amniotic fluid and cervical samples at caesarean birth
- Journal of Chongqing Medical University Issue 2, Pages: 142-143(2000)
- 作者机构：
  
  1. 重庆医科大学基础医学院微生物学教研室,400016
  2. 重庆市艾滋病性病防治办公室,400015
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2000.02.012
  CLC： R446.5
- Published：2000，
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[1]杨春,邝富国,朱道银.从剖宫者产羊水和宫颈标本中检出沙眼衣原体的研究[J].重庆医科大学学报,2000(02):142-143+161.

Detection of chlamydia trachomatis from amniotic fluid and cervical samples at caesarean birth. [J]. Journal of Chongqing Medical University (2):142-143(2000)
[1]杨春,邝富国,朱道银.从剖宫者产羊水和宫颈标本中检出沙眼衣原体的研究[J].重庆医科大学学报,2000(02):142-143+161. DOI： 10.13406/j.cnki.cyxb.2000.02.012.

Detection of chlamydia trachomatis from amniotic fluid and cervical samples at caesarean birth. [J]. Journal of Chongqing Medical University (2):142-143(2000) DOI： 10.13406/j.cnki.cyxb.2000.02.012.

摘要

目的 :本文通过检查配对母胎标本中的沙眼衣原体（Ct）

拟探讨Ct垂直传播的机制。方法 :应用细胞培养

聚合酶链反应（PCR）检查配对母胎标本（宫颈、羊水、新生儿睑结膜）中的沙眼衣原体（Ct）。结果 :10 2例剖宫产配对母胎标本中

宫颈、羊水、新生儿睑结膜均为阳性有 2 4例。宫颈阴性、羊水、新生儿睑结膜阳性共 6例。宫颈阳性、羊水、新生儿睑结膜阴性共4例。宫颈、羊水、新生儿睑结膜均为阴性有 6 8例。孕妇的Ct感染率 2 7.5 % （2 8/ 10 2 ）

胎儿的Ct感染率为 2 9.4% （30 / 10 2 ）。结论 :Ct宫颈感染与羊水细胞感染有非常显著的相关性（P <0 .0 0 5 ）。孕妇的Ct感染可导致胎儿感染

其感染方式主要是通过宫颈逆行引起宫内感染

Abstract

Objective: To study the modes and routes of the vertical Chlamydia trachomatis(Ct) transmission. Methods:Chlamydia trachomatis in the matched maternal-fetal samples(cervices

amniotic fluid and neonatal conjunctivas) was detected by cell culture and polymerase chain reaction(PCR). Results:Of the 102 matched maternal-fetal samples at caesarean birth

24 matched samples of cervices

amniotic fluid and neonatal conjunctivas were positive for Ct by cell culture and PCR; 6 were negative for cervices but positive for amniotic fluid and neonatal conjunctivas; 4 were positive for cervices but negative for amniotic fluid and neonatal conjunctivas; 68 were negative for cervices

amniotic fluid

and neonatal conjunctivas. The Ct transmission rates of pregnant women and newborns were 27.5%(28/102) and 29.5%(30/102)

respectively. Conclusion:Cervical Chlamydia infection was highly related to the amniotic infection.The Ct infection in pregnant women may cause fetal infection and the pathways of intrauterine infection seem to be ascension from cervical access to the amniotic cavity.

关键词

沙眼衣原体PCR羊水

Keywords

Chlamydia trachomatisPolymerase chain reaction(PCR)Amniotic fluid

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Related Institution

Department of Neonatology,the Children’s Hospital,Chongqing Medical University

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重庆医科大学儿科学院外科实验室

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