Serum, TNF-α level in Grave’s disease patient

JIANG Hai-yan; et al

doi:10.13406/j.cnki.cyxb.2000.01.016

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Serum, TNF-α level in Grave’s disease patient

更新时间：2024-01-17

- Serum, TNF-α level in Grave’s disease patient
- Journal of Chongqing Medical University Issue 1, Pages: 47-49(2000)
- 作者机构：
  
  重庆医科大学第二临床院核医学科,400010
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2000.01.016
  CLC： R581.1
- Published：2000，
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[1]姜海燕,王进军,张万钟.Grave’s病患者血清肿瘤坏死因子的研究[J].重庆医科大学学报,2000(01):47-49.

JIANG Hai-yan, et al. Serum, TNF-α level in Grave’s disease patient. [J]. Journal of Chongqing Medical University (1):47-49(2000)
[1]姜海燕,王进军,张万钟.Grave’s病患者血清肿瘤坏死因子的研究[J].重庆医科大学学报,2000(01):47-49. DOI： 10.13406/j.cnki.cyxb.2000.01.016.

JIANG Hai-yan, et al. Serum, TNF-α level in Grave’s disease patient. [J]. Journal of Chongqing Medical University (1):47-49(2000) DOI： 10.13406/j.cnki.cyxb.2000.01.016.

摘要

本文检测了４５例ＧＤ，１００例健康对照组血清ＴＮＦ－α水平，结果ＧＤ患者血清ＴＮＦ－α水平显著升高（Ｐ＜０．０１）。与其ＦＴ３，ＦＴ４，ＴＧＡＢ，ＴＭＡＢ水平及其甲吸率无相关性。升高的水平与病程长短和甲状腺大小有关。ＧＤ患者１３１Ｉ治疗前后血清：ＦＮＦ－α水平无明显变化，（１３１）

Ｉ

治疗后不同效果组治疗前血清ＴＮＦ－α水平无明显差异。表明ＧＤ患者血清ＴＮＦ－α水平升高；ＧＤ的“功能缓解”与“免疫缓解”不同步；ＴＮＦ－α不影响ＧＤ患者对碘的摄取及其对腆的敏感性。

Abstract

Serum TNF- α level in 45 GD Patients and 100 cases of control were studied. The results showed that the TNF- α level in GD patients was significantly higher (P<0.01)than in the controls and correlated to the course of the disease & the mass of the thyroid

but not to FT3

FT4

TGAB

TMAB levels and thyroid absorption rate of 131I. There was no difference TNF-α levels of GD patients before and after131I treatment.As well the TNF- α level did not affect treafment effectivebess.The cesults indicat that the level of TNF- α in GD is elevated.Furthermore "func nonal moderation" and "immuno moderation" are not synchronous.TNF- α does not affect the iodine absorption and sensitivity in patients.

关键词

Graves病131碘治疗TNF-α

Keywords

GD(131)~I treatmentTNF- a

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