Specific IgE and specific IgG subclasses in allergic rhinitis

Hong Sulin

doi:10.13406/j.cnki.cyxb.1999.03.017

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Specific IgE and specific IgG subclasses in allergic rhinitis

更新时间：2024-01-17

- Specific IgE and specific IgG subclasses in allergic rhinitis
- Journal of Chongqing Medical University Issue 3, Pages: 270-272(1999)
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- DOI：10.13406/j.cnki.cyxb.1999.03.017
  CLC： R765.21
- Published：1999，
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[1]洪苏玲.日本杉特异性IgE,IgG亚类在鼻变态反应中的诊断意义[J].重庆医科大学学报,1999(03):270-272.

Hong Sulin. Specific IgE and specific IgG subclasses in allergic rhinitis. [J]. Journal of Chongqing Medical University (3):270-272(1999)
[1]洪苏玲.日本杉特异性IgE,IgG亚类在鼻变态反应中的诊断意义[J].重庆医科大学学报,1999(03):270-272. DOI： 10.13406/j.cnki.cyxb.1999.03.017.

Hong Sulin. Specific IgE and specific IgG subclasses in allergic rhinitis. [J]. Journal of Chongqing Medical University (3):270-272(1999) DOI： 10.13406/j.cnki.cyxb.1999.03.017.

摘要

观察120例日本杉花粉过敏鼻炎病人的总IgE，特异性IgE，总IgG及特异性IgG亚类水平。结果表明，病人特异性IgE（30．60±0．78iu／ml）明显高于对照组（0.64±0．16iu／ml）（p＜0．01），特异性IgG4水平，病人组（478．88±120．60ng／ml）与对照组（284．90±118．10ng／ml）亦有显著差异（P＜0．01），特异性IgG2比较也有显著差异（病人组457．46±136．65ng／ml，对照组203．44±110．70ng／ml）（P＜0．01），治疗后病人组特异性IgE水平下降（治疗前30．60±0．78iu／ml，治疗后1．58±0．44iu／ml，P＜0．01），特异性IgG4水平也下降（治疗前478．88±120．60ng／ml，治疗后292.10±101．18ng／ml，P＜0．01），均存在显著差异，提示特异性IgG亚类在Ⅰ型变态反应的诊断作用中具有明显的特异性及敏感性。

Abstract

Using enzyme-linked immunosorbent assay

we detected the levels of total IgE

Japanese cedar specificIgE

and Japanese cedar specific IgG subcalass in 120 patients with Japanese cedar allergic rhinitis.The resultsshowed that the levels of SIgG4(478.88±120.60ng/ml) of patients were significantly higher than those of thecontrols(P＜0.01)

and the same results were found for concentrations of specific IgG2 and IgG4.The differecebetween before-treatment and after-treatment levels of specifie IgE and specific IgG4 was also significant(specific IgE before treatment.30.60±0.78iu/ml

after treatment:1.58±0.44iu/ml P＜0.01

specific IgG4 before treat.mentt478.88±120.60ng/ml

after treatment.292.10±101.18ng/ml P＜0.01).We conclude that specific IgG subclasseshave obvious etiological specificity and sensitivity.

关键词

日本杉特异性IgE特异性IgG亚类

Keywords

Japanese cedarSpecific IgESpecific IgG subclass

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