A new tumor marker TAG-72 and its value in diagnosis of gastric carcinoma

doi:10.13406/j.cnki.cyxb.1998.04.034

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A new tumor marker TAG-72 and its value in diagnosis of gastric carcinoma

更新时间：2024-01-17

- A new tumor marker TAG-72 and its value in diagnosis of gastric carcinoma
- Journal of Chongqing Medical University Issue 4, Pages: 349-351(1998)
- 作者机构：
  
  1. 重庆医科大学临床学院普外科
  2. 重庆医科大学临床学院普外科博士生
  3. 重庆医科大学临床学院普外科重庆医科大学临床学院普外科博士生
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1998.04.034
  CLC： R735.2
- Published：1998，
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[1]邓小康,张才全.血清肿瘤相关糖蛋白抗原(TAG-72)测定对胃癌诊断价值的评价[J].重庆医科大学学报,1998(04):349-351.

A new tumor marker TAG-72 and its value in diagnosis of gastric carcinoma. [J]. Journal of Chongqing Medical University (4):349-351(1998)
[1]邓小康,张才全.血清肿瘤相关糖蛋白抗原(TAG-72)测定对胃癌诊断价值的评价[J].重庆医科大学学报,1998(04):349-351. DOI： 10.13406/j.cnki.cyxb.1998.04.034.

A new tumor marker TAG-72 and its value in diagnosis of gastric carcinoma. [J]. Journal of Chongqing Medical University (4):349-351(1998) DOI： 10.13406/j.cnki.cyxb.1998.04.034.

摘要

本文评价了一种新的肿瘤标志物 TAG-72的测定在诊断胃癌中的价值。用放射免疫法（CA72-4RIA）测定了30例胃癌患者与10例良性胃疾病患者进行的 CA72-4水平

其诊断胃癌的阳性率为43%

特异性为100%。在早期与进展期胃癌组中

敏感性与均值均有显著性差异（P<0.05）。在伴有淋巴结转移与无淋巴结转移的胃癌患者中

CA72-4均值也有显著性差异（P<0.05）。这表明 TAG-72是诊断胃癌的可靠标志物

特异性极高

对胃癌的诊断、临床分期及淋巴结转移的预测有一定意义。

Abstract

This article evaluated the serum levels of a new tumor marker TAG-72 in diagnosis of gastric cancinoma. Serum tumor marker CA72-4 were measured in 30 patients with gastric carcinomas and 10 with benign gastric disorders.CA72-4 had sensitivities of 43% and specifcity of 100% for gastric carcinomas.CA72-4 can significantly separate stage Ⅰ disease from stage Ⅱ Ⅲ Ⅳ disease(P<0.05)CA72-4 also gave differentiation bwtween patients with positive and negative nodes(P<0.05).These preliminary findings indicate that TAG-72 is a reliable tumor marker of disease stage and activity in gastric cancer.Further longitudinal studies are repuired for full evaluation of its clinical utility.

关键词

胃癌肿瘤标志物TAG-72

Keywords

Gastric neoplasmtumor markerTAG72

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