CLINICAL SIGNIFICANCE OF BETA-2 MICROGLOBULIN IN BLADDER CANCER

doi:10.13406/j.cnki.cyxb.1992.04.010

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CLINICAL SIGNIFICANCE OF BETA-2 MICROGLOBULIN IN BLADDER CANCER

更新时间：2024-01-17

- CLINICAL SIGNIFICANCE OF BETA-2 MICROGLOBULIN IN BLADDER CANCER
- Journal of Chongqing Medical University Issue 4, Pages: 287-291(1992)
- 作者机构：
  
  1. 重庆医科大学第一医院泌尿外科
  2. 重庆医科大学核医学科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1992.04.010
  CLC：
- Published：1992，
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[1]刘朝东,何梓铭,罗加,吴国桢.测定β_2-微球蛋白对膀胱癌患者的临床意义[J].重庆医科大学学报,1992(04):287-291.

CLINICAL SIGNIFICANCE OF BETA-2 MICROGLOBULIN IN BLADDER CANCER. [J]. Journal of Chongqing Medical University (4):287-291(1992)
[1]刘朝东,何梓铭,罗加,吴国桢.测定β_2-微球蛋白对膀胱癌患者的临床意义[J].重庆医科大学学报,1992(04):287-291. DOI： 10.13406/j.cnki.cyxb.1992.04.010.

CLINICAL SIGNIFICANCE OF BETA-2 MICROGLOBULIN IN BLADDER CANCER. [J]. Journal of Chongqing Medical University (4):287-291(1992) DOI： 10.13406/j.cnki.cyxb.1992.04.010.

摘要

本文报告34例膀胱癌

13例其它恶性肿瘤

15例下尿路感染

21例正常人用放射免疫法测定血、尿β

-微球蛋白（β

-MG）及尿/血β

-MG比值的结果

发现膀胱癌组尿β

-MG值显著高于其它任何一组

其增高者（

240μg/L）占79%.尿β

-MG及尿/血β

-MG比值随肿瘤的分期、分级增加而增高.作者讨论了影响测定β

-MG的因素和测定β

-MG的临床意义

认为尿β

-MG升高可能由于肿瘤细胞释放β

-MG到尿里.测定尿β

-MG对诊断膀胱癌或血尿的鉴别诊断有重要意义

也可能对术前估计肿瘤的恶性程度

术后监测肿瘤复发有一定意义

Abstract

The urinary(U)

serum(S) β2 microglobul in (β2-MG) and its U/S ratio Were studied in patients with bladder carcinoma(34)

non-bladder neoplasms(13)

lower urinary tract infections( 15) and normal subjects(21) by radioimmunoassay. The urinary β2-MG levels in patients with bladder carcinoma (>240 μg/L

79%were significantly higher than other groups(P<0.01). The elevated urinary (β2-MG value corresponds to the increase in tumor stage that urinary β2-MG value elevated in bladder carcinoma were discussed. It was considered that high value of the urinary β2-MG in patients with bladder carcinoma may by released by the tumor cell itself. Therefore

the urinary β2-MG will have a practical importance in patients with bladder carcinoma or hematuria for the diagnosis and could also contribute to the biochemical monitoring of bladder carcinoma as a marker for estimating preo-peratively malignancy and detecting postoperatively recurence

关键词

膀胱癌β2-微球蛋白

Keywords

bladder cancer2-Microylobumin

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