DIAGNOSTIC; VALUE OF SERUM SIALIC ACID, FUCO SE AND ACUTE PHASE PROTEINS MEASUREMENT IN PATIENTS WITH DIGESTIVE TRACT CANCER

Rong Xuemin et al Department of Pathology Chongqing Staffs Medical College

doi:10.13406/j.cnki.cyxb.1992.01.008

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DIAGNOSTIC; VALUE OF SERUM SIALIC ACID, FUCO SE AND ACUTE PHASE PROTEINS MEASUREMENT IN PATIENTS WITH DIGESTIVE TRACT CANCER

更新时间：2024-01-17

- DIAGNOSTIC; VALUE OF SERUM SIALIC ACID, FUCO SE AND ACUTE PHASE PROTEINS MEASUREMENT IN PATIENTS WITH DIGESTIVE TRACT CANCER
- Journal of Chongqing Medical University Issue 1, Pages: 34-37(1992)
- 作者机构：
  
  1. 重庆职工医学院病理教研室
  2. 重庆医科大学病理生理教研室
  3. 重庆市急救医疗中心消化科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1992.01.008
  CLC：
- Published：1992，
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[1]荣学明,帅兆春,杨小健,王靖伦,段积华,段红,卿光勤,曾庆贵.血清唾液酸、岩藻糖和急性期蛋白测定对消化道癌症的诊断价值[J].重庆医科大学学报,1992(01):34-37.

Rong Xuemin et al Department of Pathology Chongqing Staffs Medical College. DIAGNOSTIC; VALUE OF SERUM SIALIC ACID, FUCO SE AND ACUTE PHASE PROTEINS MEASUREMENT IN PATIENTS WITH DIGESTIVE TRACT CANCER. [J]. Journal of Chongqing Medical University (1):34-37(1992)
[1]荣学明,帅兆春,杨小健,王靖伦,段积华,段红,卿光勤,曾庆贵.血清唾液酸、岩藻糖和急性期蛋白测定对消化道癌症的诊断价值[J].重庆医科大学学报,1992(01):34-37. DOI： 10.13406/j.cnki.cyxb.1992.01.008.

Rong Xuemin et al Department of Pathology Chongqing Staffs Medical College. DIAGNOSTIC; VALUE OF SERUM SIALIC ACID, FUCO SE AND ACUTE PHASE PROTEINS MEASUREMENT IN PATIENTS WITH DIGESTIVE TRACT CANCER. [J]. Journal of Chongqing Medical University (1):34-37(1992) DOI： 10.13406/j.cnki.cyxb.1992.01.008.

摘要

本文测定了55例消化道癌症患者、61例消化道良性疾病患者和58例健康献血员血清唾液酸、岩藻糖和五种急性期蛋白的含量

结果发现癌症组血清唾液酸、岩藻糖、α

-酸性糖蛋白（α

-AG）、α

-抗胰蛋白酶（α

-AT）和结合珠蛋白（HP）的浓度显著高于正常人及良性疾病组（P

0.01）

并且

唾液酸、岩藻糖浓度的增高与急性期蛋白呈明显的正相关.本实验结果表明血清唾液酸、岩藻糖、α

-AG、α

-AT和HP可以作为消化道癌症的肿瘤标志物;检测上述生化指标

特别是联合检测血清唾液酸、岩藻糖和α

-AG

对消化道癌症患者有辅助诊断价值

Abstract

S’. rum sialic acid(SA)

fucost(Fuc) and five acute phase proteins were measured in 55 patients with digestive tract cancer(DTC)

61 with digestive tract bengin diseases and 58 hcalihy blood donors. The serum concentrations of SA

Fuc

α1-acid glycoprotcin(α1-AG)

α1-antitrypsin(α1-AT) and haptoglobin (HP) were significantly elevated in the patients with cancer as compared with the control group(P<0.01). The raised concentrations of SA

Fuc in DTC usually bear a obvious positive correlations with increased concentrations of α1-AG

α1-AT and HP. The experiment results indicate that seum SA

Fuc

α1-AG

α1-AT and HP may be regarded tamer markers in DTC. Therefore

measurements of these biochemical indices .especially combined measurements of SA

Fuc and α1-AG may have diagnostic value in patients with DTC

关键词

消化道癌症唾液酸岩藻糖急性期蛋白

Keywords

Digtstiivo tract cancer (DTC)Sialic acid(SA)Fucose(Fuc)Acute phase proteins.

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