SERUM SIALIC ACID, FUCOSE AND ACUTE PHASE PROTEINS IN PATIENTS WITH NASOPH ARYNGEAL OR LARYNGEAL CARCINOMA

doi:10.13406/j.cnki.cyxb.1991.04.003

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SERUM SIALIC ACID, FUCOSE AND ACUTE PHASE PROTEINS IN PATIENTS WITH NASOPH ARYNGEAL OR LARYNGEAL CARCINOMA

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- SERUM SIALIC ACID, FUCOSE AND ACUTE PHASE PROTEINS IN PATIENTS WITH NASOPH ARYNGEAL OR LARYNGEAL CARCINOMA
- Journal of Chongqing Medical University Issue 4, Pages: 276-280(1991)
- 作者机构：
  
  1. 重庆医科大学第一医院耳鼻喉科
  2. 重庆医科大学病理生理教研室
  3. 重庆医科大学生化教研室
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1991.04.003
  CLC：
- Published：1991，
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[1]陈佩君,魂莲枝,王丽洪,陈鸿雁,袁兴玉,段积华,王贤辅.鼻咽癌喉癌患者血清唾液酸岩藻糖和急相蛋白含量观察[J].重庆医科大学学报,1991(04):276-280.

SERUM SIALIC ACID, FUCOSE AND ACUTE PHASE PROTEINS IN PATIENTS WITH NASOPH ARYNGEAL OR LARYNGEAL CARCINOMA. [J]. Journal of Chongqing Medical University (4):276-280(1991)
[1]陈佩君,魂莲枝,王丽洪,陈鸿雁,袁兴玉,段积华,王贤辅.鼻咽癌喉癌患者血清唾液酸岩藻糖和急相蛋白含量观察[J].重庆医科大学学报,1991(04):276-280. DOI： 10.13406/j.cnki.cyxb.1991.04.003.

SERUM SIALIC ACID, FUCOSE AND ACUTE PHASE PROTEINS IN PATIENTS WITH NASOPH ARYNGEAL OR LARYNGEAL CARCINOMA. [J]. Journal of Chongqing Medical University (4):276-280(1991) DOI： 10.13406/j.cnki.cyxb.1991.04.003.

摘要

本文测定94例鼻咽癌、65例喉癌患者血清唾液酸、岩藻糖、前清蛋白（PA）、α

—抗胰蛋白酶（α

—AT）、α

—酸性糖蛋白（α

—AGP）、触珠蛋白（HP）和转铁蛋白（TF）含量.逐步判别分析法对上述测定项目进行筛选

结果发现:对鼻咽癌、喉癌早期诊断有意义的指标是PA、α

—AT、α

—AGP、HP和TF

对治疗后未复发与复发判别有意义的指标是唾液酸

—AT、α

—AGP和HP;由计算机分别得出早期诊断和判别治疗后有无复发之判别函数式.将本组病例之测定值

分别回代入上述判别函数式

临床诊断与判别结果之符合率均在80%以上.结果表明:血清唾液酸和急相蛋白测定

有助于鼻咽癌

喉癌之早期诊断和治疗后随访

Abstract

Serum concentrations of sialic acid

fucose

prealbumin(PA )

α1-antitrypsin (α1-AT)

α1-acid glycoproteins(α1-AGP)

haptoglobin (HP) and transferrin (TF) were measured in 94 nasopharyngeal carcinoma and 65 cancer of larynx. Statistical evalution was made with stepwise discriminant analysis

and the discriminant functions were obtained. The effectiveness of allocation were examined on every one of all patients in the original data

Our results suggested

with the discriminant function equation consisting of serum PA

α1-AT

α1-AGP

HP and TF concentrations we could best separate the patients sufferng from nasopharyngeal or laryngeal carcinoma from the normal; the effective rate of discriminant was 87.36% and 88% for nasopharyngeal carcinoma from normal and laryngeal carcin-oma from normal respectively. However using discriminant function equation

composed of serum sialic acid

PA and α1-AT

we could also discriminate nasopharyngeal or laryngeal carcinoma with recurrence from the one with non-recurrence

the effective rate of discriminant was 93.1% and 80% for nasopharyngeal carcinoma and cancer of larynx respectively

关键词

鼻咽癌喉癌唾液酸岩藻糖急相蛋白

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