CHROMOSOME ANALYSIS OF ENDOMETRIUM BEFORE AND AFTER CLOMIPHENE THERAPY

Peng Lin et al Dept. of Obstefrics and Gynecology

doi:10.13406/j.cnki.cyxb.1991.04.002

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CHROMOSOME ANALYSIS OF ENDOMETRIUM BEFORE AND AFTER CLOMIPHENE THERAPY

更新时间：2024-01-17

- CHROMOSOME ANALYSIS OF ENDOMETRIUM BEFORE AND AFTER CLOMIPHENE THERAPY
- Journal of Chongqing Medical University Issue 4, Pages: 272-275(1991)
- 作者机构：
  
  重庆医科大学第二医院妇产科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1991.04.002
  CLC：
- Published：1991，
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[1]彭林,顾美礼.氯菧酚胺治疗前后的子宫内膜染色体分析[J].重庆医科大学学报,1991(04):272-275.

Peng Lin et al Dept. of Obstefrics and Gynecology. CHROMOSOME ANALYSIS OF ENDOMETRIUM BEFORE AND AFTER CLOMIPHENE THERAPY. [J]. Journal of Chongqing Medical University (4):272-275(1991)
[1]彭林,顾美礼.氯菧酚胺治疗前后的子宫内膜染色体分析[J].重庆医科大学学报,1991(04):272-275. DOI： 10.13406/j.cnki.cyxb.1991.04.002.

Peng Lin et al Dept. of Obstefrics and Gynecology. CHROMOSOME ANALYSIS OF ENDOMETRIUM BEFORE AND AFTER CLOMIPHENE THERAPY. [J]. Journal of Chongqing Medical University (4):272-275(1991) DOI： 10.13406/j.cnki.cyxb.1991.04.002.

摘要

研究了用直接法制备子宫内膜细胞染色体的技术及细胞分裂相与组织学分期的关系.结果显示直接法制备子宫内膜细胞染色体成功率为40.3%

增生期与分泌期子宫内膜组织的分裂相出现率统计学上无显著性差别.用子宫内膜细胞染色体畸变率分析方法对服用氯菧酚胺的妇女于用药前、用药三月、用药六月作子宫内膜细胞染色体的自身对照研究

结果提示氯菧酚胺对用药妇女子宫内膜无可察觉的致突变、致癌的遗传学效应

Abstract

This article presents a technique of chromosome analysis which are prepared from human endometrium directly. The success rate was 40.3%. It was shown that there was no statistical significant differences between mitotic index of prolifera-tive and secretory phases. The same study had been carried out in women before and had been taking clomiphene for 3 cycles and 6 cycles. And also no detectable mutagenic

and no carcinogenic effects on endometrium were found

关键词

氯菧酚胺子宫内膜染色体

Keywords

ClomipheneendometriumChromosome

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Related Institution

Department of Obstetrics and Gynecology,University-Town Hospital of Chongqing Medical University

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