DIAGNOSTIC VALUE OF SERUM SIALIC ACID, FUCOSE AND AGUTE PHASE PROTEINS MEASUREMENT IN PATIENTS WITH AFP NEGATIVE PRIMARY HEPATOCELLULAR CARCINOMA

Duan Jihua et al Department of Pathophysiology

doi:10.13406/j.cnki.cyxb.1991.04.001

您当前的位置：

首页 >

文章列表页 >

DIAGNOSTIC VALUE OF SERUM SIALIC ACID, FUCOSE AND AGUTE PHASE PROTEINS MEASUREMENT IN PATIENTS WITH AFP NEGATIVE PRIMARY HEPATOCELLULAR CARCINOMA

更新时间：2024-01-17

- DIAGNOSTIC VALUE OF SERUM SIALIC ACID, FUCOSE AND AGUTE PHASE PROTEINS MEASUREMENT IN PATIENTS WITH AFP NEGATIVE PRIMARY HEPATOCELLULAR CARCINOMA
- Journal of Chongqing Medical University Issue 4, Pages: 267-271(1991)
- 作者机构：
  
  1. 重庆医科大学病理生理学教研室
  2. 重庆职工医学院病理教研室
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1991.04.001
  CLC：
- Published：1991，
扫描看全文
[1]段积华,段红,郑维萍,陈思秀,荣学明.血清SA、Fuc、APP测定对AFP(-)HCC的诊断价值[J].重庆医科大学学报,1991(04):267-271.

Duan Jihua et al Department of Pathophysiology. DIAGNOSTIC VALUE OF SERUM SIALIC ACID, FUCOSE AND AGUTE PHASE PROTEINS MEASUREMENT IN PATIENTS WITH AFP NEGATIVE PRIMARY HEPATOCELLULAR CARCINOMA. [J]. Journal of Chongqing Medical University (4):267-271(1991)
[1]段积华,段红,郑维萍,陈思秀,荣学明.血清SA、Fuc、APP测定对AFP(-)HCC的诊断价值[J].重庆医科大学学报,1991(04):267-271. DOI： 10.13406/j.cnki.cyxb.1991.04.001.

Duan Jihua et al Department of Pathophysiology. DIAGNOSTIC VALUE OF SERUM SIALIC ACID, FUCOSE AND AGUTE PHASE PROTEINS MEASUREMENT IN PATIENTS WITH AFP NEGATIVE PRIMARY HEPATOCELLULAR CARCINOMA. [J]. Journal of Chongqing Medical University (4):267-271(1991) DOI： 10.13406/j.cnki.cyxb.1991.04.001.

摘要

本文对31例血清甲胎蛋白（AFP）阳性原发性肝细胞性肝癌（HCC）、33例AFP（—）HCC、35例肝硬化和58例正常献血清唾液酸（SA）、岩藻糖（Fuc）及五种急性期蛋白（APP）[a

-酸性糖蛋白（a

-AG）、结合珠蛋白（HP）、a

-抗胰蛋白酶（a

-AT）、前白蛋白（PA）和转铁蛋白（TF）]同时进行测定.结果表明AFP（—）肝癌组患者血清SA、Fuc、a

-AG、HP及a

-AT均显著高于对照组

其中

Fuc、a

-AG与HP又比AFP（+）肝癌组为高.因此可将上述五项指标视为AFP（—）肝癌患者血清肿瘤标志物.此外

还发现肝癌患者血清两种结合蛋白的糖类含量高与血清a

-AG、HP和a

-AT呈明显地正相关

Abstract

Serum concentrations Of sialic acid(SA)

fucose (Fuc)

α1-acid glycoprotein (α1-AG)

haptoglobi (HP)

α1-antitrypsin (α1-AT)

Prealbumin (PA) and tranrf-errin (TF)were co comitantly measured in 31 patier’s with AFP negative primary hepatocellular carcinoma (HCC)

33 with AFP positive HCC

35 with cirrhosis and 58 normal blood donors. The results revealed that serum SA

Fuc

α1-AG

HP and α1-AT levels were all significantly higher in patients with AFP negative HCC than in control groups. Among them

Fuc

α1-AG and HP levels were significantly higher in patients with AFP negative HCC than in AFP positive HCC. Therefore

measurements of these five indices are suggested in the diagnosis of the AFP negative HCC.Furtheremore

the raised concentration of protein bound sugars in HCC usually bear a strong positive correlation with increased concentrations of serum α1-AG

HP and α1-AT

关键词

原发性肝细胞性肝癌甲胎蛋白唾液酸岩藻糖急性期蛋白α1-酸性糖蛋白结合珠蛋白α1-抗胰蛋白酶前白蛋白转铁蛋白

Keywords

Primary Hepatocellular Carcinoma (HCC)α-Fetoprotein(AFP)sialic Acid (SA)Fucose (Fuc)Acute Phase Protein (APP)α1-Acid Glycoprotein (α1-AG)Haptoglobin (HP)α1-Antitrypsin (α1-AT)Prealbumin(PA)Transferria(TF)

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

⁰