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重庆医科大学第二医院药剂科
Published:1991,
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[1]滕裕丰,姜成莉.KIn配离子的溶解度测定[J].重庆医科大学学报,1991(03):248-250.
DETERMINATION OF THE SOLUBILITY OF KIn- COMPLEX ION. [J]. Journal of Chongqing Medical University (3):248-250(1991)
[1]滕裕丰,姜成莉.KIn配离子的溶解度测定[J].重庆医科大学学报,1991(03):248-250. DOI: 10.13406/j.cnki.cyxb.1991.03.024.
DETERMINATION OF THE SOLUBILITY OF KIn- COMPLEX ION. [J]. Journal of Chongqing Medical University (3):248-250(1991) DOI: 10.13406/j.cnki.cyxb.1991.03.024.
碘(I
2
)在水中的溶解度为1:3000
与不同比例的碘化钾(KI)生成络合物后
测得I在KI
3
-
、KI
5
7
系列水溶液中的溶解度/可溶浓度依次为1:2/50%、1:4.5/22.22%、1:7.9/12.66%.难溶物(I
)的溶解度与助溶剂(KI)的用量呈直线关系
γ=0.9984
y=1.74x-6.5.本文提示
以KI
1
溶液配制碘酊(碘酒)
则可将I
与KI二者用量之比
由中国药典(“药典”)的1:0.75、中国医院制剂规范(“规范”)的1:0.6
药物制剂注解(“注解”)的1:0.4降为1:0.22
从而可最大限度减少KI对组织的刺激性
亦可节省KI
The solubitily of Iodine [I2] in water is 1:3000. After forming complex compounds of iodine with different proportions of KI
the solubitity and the dissolved concentration of iodine in series of solutions of KI3-
KI5- and KI7- were determined as 1:2/50%
1:4.5/22.22% and 1:7.9/12.66% respectively.The solubility of dysalbyrmire [I2] forms linear relation with the quantity of flux [KI]
y=1.74x-8.5
r = 0.9984.The result of the experiment points out that in preparing iodine tincture
the proportion of iodine to KI can be reduced from (he 1:0.75 of the Pharmcopeia
the 1:0.6 of the Standardization and the 1:0
4 of the annotation to the 1:0.22
the irri-taion of the KI against the tissue can also be reduced to a minimum
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