HEMOSTATIC ABNORMALITIES AND ENAOTOXEMIA IN HEPATIC CIRRHOSIS

doi:10.13406/j.cnki.cyxb.1991.02.003

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HEMOSTATIC ABNORMALITIES AND ENAOTOXEMIA IN HEPATIC CIRRHOSIS

更新时间：2024-01-17

- HEMOSTATIC ABNORMALITIES AND ENAOTOXEMIA IN HEPATIC CIRRHOSIS
- Journal of Chongqing Medical University Issue 2, Pages: 101-105(1991)
- 作者机构：
  
  重庆医科大学第二医院内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1991.02.003
  CLC：
- Published：1991，
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[1]戴立里,徐葆元,刘祥贵,高杰,何生玉.肝硬化患者凝血障碍与内毒素血症[J].重庆医科大学学报,1991(02):101-105.

HEMOSTATIC ABNORMALITIES AND ENAOTOXEMIA IN HEPATIC CIRRHOSIS. [J]. Journal of Chongqing Medical University (2):101-105(1991)
[1]戴立里,徐葆元,刘祥贵,高杰,何生玉.肝硬化患者凝血障碍与内毒素血症[J].重庆医科大学学报,1991(02):101-105. DOI： 10.13406/j.cnki.cyxb.1991.02.003.

HEMOSTATIC ABNORMALITIES AND ENAOTOXEMIA IN HEPATIC CIRRHOSIS. [J]. Journal of Chongqing Medical University (2):101-105(1991) DOI： 10.13406/j.cnki.cyxb.1991.02.003.

摘要

本文通过多项止凝血实验指标和鲎试验对20例失代偿性肝硬化患者进行动态观察

发现血浆内毒素水平和ⅧR:Ag均增高.其他凝血因子和ATⅢ减低.纤维蛋白连接素减低.结果提示:（1）止凝血功能障碍与内毒素血症（ETM）并存

并与疾病的进展密切有关;（2）ETM的发生率和严重程度与肝硬化失代偿的程度有关;（3）ETM和止凝血功能异常的动态观察可作为判断预后的一项参考指标

Abstract

A follow-up study of the dynamic changes with multiple parameters of blood coagulation and plasma limulus assay was carried out in 20 patients with decompen-sated hepatic cirrhosis.It was found that the levels of endotoxin in peripheral blood and factor VIII-related antigen increased significantly

prothrombin time and kaolin partial thromboplastin time prolonged

whereas fibrinogen

factor II

hepaplastin test

antithrombin-III and fibronectin decreased.Our data suggested that( 1 )both the coagulation abnormalities and endotoxemia were coexisted and correlated progressively with the disease process. ( 2 )the incidence and severity of endotoxemia were closely correlated with the degree and severity of hepatic decompensation; ( 3 )dynamic charges of endotoxemia and coagulation abnormalities were of some prognostic significance in decompensated hepatic cirrhosis

关键词

凝血异常鲎试验内毒素血症纤维蛋白连接素

Keywords

Coagulation abnormalitiesLimulus lysated assayendotoxemiaFibronectin

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Department of General Surgery,College of Clinical Medicine,Chongqing Medical University

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Department of Anesthesiology，the Children’s Hospital，Chongqing Medical University，Key Laboratory of Child Development and Disorders Co-founded by Provincial Government and Ministry of Education，Key Laboratory of Pediatrics in Chongqing，Chongqing International Science and Technology Cooperation Center for Child Development and Disorders

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