Chromosomes in peripheral blood lymphocytes of 45 patients with ovarian tumour and 10 normal subjects of control were examined. The results demonstrated that the frequencies of sister chromatid exchange (SCE)

micronucleus and fragility of the malignant group were significantly higher than those of the benign group and of the controls. And the fragile sites with the highest frequencies were located between 6ql5 and 6q24. The carcinogenesis and prognosis of ovarian carcinoma were also briefly disussed