RESEARCH INTO PHARMACODYNAMICS OF BIFONAZOLE

Luo Donghui; et al

doi:10.13406/j.cnki.cyxb.1990.04.003

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RESEARCH INTO PHARMACODYNAMICS OF BIFONAZOLE

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- RESEARCH INTO PHARMACODYNAMICS OF BIFONAZOLE
- Journal of Chongqing Medical University Issue 4, Pages: 265-268(1990)
- 作者机构：
  
  重庆医科大学第一医院皮肤科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1990.04.003
  CLC：
- Published：1990，
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[1]罗东辉,袁承晏.联苯苄唑的药效学研究实验室抗真菌活性测定[J].重庆医科大学学报,1990(04):265-268.

Luo Donghui, et al. RESEARCH INTO PHARMACODYNAMICS OF BIFONAZOLE. [J]. Journal of Chongqing Medical University (4):265-268(1990)
[1]罗东辉,袁承晏.联苯苄唑的药效学研究实验室抗真菌活性测定[J].重庆医科大学学报,1990(04):265-268. DOI： 10.13406/j.cnki.cyxb.1990.04.003.

Luo Donghui, et al. RESEARCH INTO PHARMACODYNAMICS OF BIFONAZOLE. [J]. Journal of Chongqing Medical University (4):265-268(1990) DOI： 10.13406/j.cnki.cyxb.1990.04.003.

摘要

联苯苄唑是一种新的咪唑类衍生物

具有广谱抗真菌作用。本实验采用100株临床常见的真菌作了MIC测定。这些菌株对联苯苄唑普遍敏感

79%的菌株MIC≤4μg/ml。MIC值的大小受接种菌量的影响

接种量越大

MIC值越大。通过实验对比

联苯苄唑与咪康唑的抗真菌活性相近

Abstract

Bifonazole is a new imidazolyl derivative

with broad spectrum anlimycotic activity. In our experiment

100 strains of common dermatophytes in clinical practice were used to evaluate the MIC of Bifonazole. All the species tested

were sensitive to this agent

and the MIC values of 79% of strains were under 4g/ml. The MIC value was influenced by inoculum size

the larger the inoculum size

the larger the MIC value. It was found that the efficacy of Bifonazole is comparable to Mico-nazole

关键词

联苯苄唑抗真菌药药效学

Keywords

BifonazoleAntimycoticPharmacodynamics

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Related Institution

Department of Anesthesia,Xinqiao Hospital,Third Military Medical University

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