The authors reported 50 cases of neurologic manifestations in 166 patients with systemic lupus erythematoses (SLE)

which showed orderly as mental disorders

seizure

headache

optic nerve lesions

cranial nerve palsy

hemiplegia

peripheral neuropathy

myopathy

pseudobulbar palsy

tremor

paraplegia and urinary incontinence. The lesions involved central nerve system

peripheral nerve system and muscular system

one patient might show lesions in more than one part of his body. To diagnose SLE was very difficulty in the early stage of this disease when there were manifestations of nerve system lesion only. When one young woman who has manifestations of nerve lesions was excluded to be ill with other diseases

the possibility of SLE may be considered. The authors reviewed the literature and the pathogencsis of these eomlications and tried to inquire into it further