PRELIMINARY INVESTIGATION ON THE DETERMINATION OF β-ADRENOCEPTORS IN RAT UTERUS DURING OESTROUS CYCLE

Shen Zhifang; et al

doi:10.13406/j.cnki.cyxb.1989.04.007

您当前的位置：

首页 >

文章列表页 >

PRELIMINARY INVESTIGATION ON THE DETERMINATION OF β-ADRENOCEPTORS IN RAT UTERUS DURING OESTROUS CYCLE

更新时间：2024-01-17

- PRELIMINARY INVESTIGATION ON THE DETERMINATION OF β-ADRENOCEPTORS IN RAT UTERUS DURING OESTROUS CYCLE
- Journal of Chongqing Medical University Issue 4, Pages: 287-290(1989)
- 作者机构：
  
  1. 重庆医科大学生殖生理教研室
  2. 重庆医科大学核医学教研室
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1989.04.007
  CLC：
- Published：1989，
扫描看全文
[1]沈穉芳,王荣琪,鲍安铮,王鼎年,梁宪生,魏莎莉.动情周期中大鼠子宫β肾上腺素能受体测定的初步研究[J].重庆医科大学学报,1989(04):287-290.

Shen Zhifang, et al. PRELIMINARY INVESTIGATION ON THE DETERMINATION OF β-ADRENOCEPTORS IN RAT UTERUS DURING OESTROUS CYCLE. [J]. Journal of Chongqing Medical University (4):287-290(1989)
[1]沈穉芳,王荣琪,鲍安铮,王鼎年,梁宪生,魏莎莉.动情周期中大鼠子宫β肾上腺素能受体测定的初步研究[J].重庆医科大学学报,1989(04):287-290. DOI： 10.13406/j.cnki.cyxb.1989.04.007.

Shen Zhifang, et al. PRELIMINARY INVESTIGATION ON THE DETERMINATION OF β-ADRENOCEPTORS IN RAT UTERUS DURING OESTROUS CYCLE. [J]. Journal of Chongqing Medical University (4):287-290(1989) DOI： 10.13406/j.cnki.cyxb.1989.04.007.

摘要

用放射配体结合技术测定了大鼠子宫肌细胞膜上β肾上腺素能受体的数目与亲和力。动情前期与动情期子宫肌β肾上腺素能受体的数目（由最大结合容量R

表示）为126.84±54.69fmol/mg蛋白质

明显高于动情后期与动情间期子宫中的数目77.98±30.66fmol/mg蛋白质（P

0.05）

由此表明子宫的激素状态可影响受体从而再影响子宫收缩。动情周期中各期间的受体亲和力（用解离常数K

反映）未见显著差别

Abstract

The number and affinity of ?-adrenoceptors on rat uterine smooth muscle membranes were determined by radioligand binding technique. The number of ?-adrenoceptors (shown by maximum binding capacity RT) of uterus in proestrus and estrus stage (126.84?54.69 fmol/mg preicin) was significantly higher than those in diestrus and metestrus stage (77.98 + 30.66 fmol/mg protein) (p<0.05). It suggests that the hormonal state of uterus may affect its receptor and thus influence the uterine contraction. There was no significant difference in affinity (shown by dissociation constant KD) among differnt stages of oestrous cycle

关键词

β肾上腺素能受体放射配体结合技术3H-双氢心得舒动情周期大鼠

Keywords

β-AdrenoceptorRadioligand Binding Technique3H-DHAOestrous Cyclerat

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Histopathological changes and pathological basis of the cryptorchidtestis in rats by maternal exposure to flutamide

DISPOSITION OF ~3H-PIPERAZINE FERULATE IN RATS

PHA INDUCED RAT T-LYMPHOCYTE TRANSFOR MATION IN VIVO

THE ALTERATIONS OF RENAL AND HEMODYNAMIC EFFECTS OF NATRIURETIC FACTOR IN ATRIA OF THE RATS WITH ACUTE HEART FAILURE

THE MODEL OF MIDDLE CEREBRAL ARTERY OCCLUSION ON SPRAGUE-DAWIEY RAT

Related Author

Peng Jinpu

Zhang Deying

Cao Xining

Zhou Yue

Shen Lianju

Long Chunlan

He Dawei

Lin Tao

Related Institution

Department of Urology,the Children’s Hospital,Chongqing Medical University,Ministry of Education Key Laboratory of Child Development and Disorders,Key Laboratory of Pediatrics in Chongqing,Chongqing International Science and Technology Cooperation Center for Child Development and Disorders

重庆医科大学基础医学部药理教研室

重庆医科大学第一医院临床药理研究室

重庆医科大学人工肝研究室

重庆医科大学病理生理学教研室

⁰