ANALYSIS OF AG-NOR AND AG-AA FOR KLINEFELTER’S SYNDROME

doi:10.13406/j.cnki.cyxb.1989.03.008

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ANALYSIS OF AG-NOR AND AG-AA FOR KLINEFELTER’S SYNDROME

更新时间：2024-01-17

- ANALYSIS OF AG-NOR AND AG-AA FOR KLINEFELTER’S SYNDROME
- Journal of Chongqing Medical University Issue 3, Pages: 199-201(1989)
- 作者机构：
  
  重庆医科大学生物教研室
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1989.03.008
  CLC：
- Published：1989，
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[1]魏若璋,彭惠民,楼宏,张静.Klinefelter综合征患者Ag-NOR及Ag-AA的分析[J].重庆医科大学学报,1989(03):199-201.

ANALYSIS OF AG-NOR AND AG-AA FOR KLINEFELTER’S SYNDROME. [J]. Journal of Chongqing Medical University (3):199-201(1989)
[1]魏若璋,彭惠民,楼宏,张静.Klinefelter综合征患者Ag-NOR及Ag-AA的分析[J].重庆医科大学学报,1989(03):199-201. DOI： 10.13406/j.cnki.cyxb.1989.03.008.

ANALYSIS OF AG-NOR AND AG-AA FOR KLINEFELTER’S SYNDROME. [J]. Journal of Chongqing Medical University (3):199-201(1989) DOI： 10.13406/j.cnki.cyxb.1989.03.008.

摘要

本文对26例Klinefelter综合征患者（16例47

xxy;10例46

xy/47

xxy）作了银染核仁形成区（Ag-NOR）及银染近端着丝粒染色体联合（Ag-AA）频率的研究

探讨X染色体数目增加与基因转录活性及不育之间的关系。结果发现无论是Ag-NOR或Ag-AA的频率均随X染色体增加而递增

xxy;46

xy/47

xxy组均与正常对照组差异极显著（P<0.001）

而47

xxy组与46

xy/47

xxy组差异显著（P<0.05）

Abstract

Observation on the frequencies of Ag-NOR and Ag-AA in the peripheral blood lymphocyte of 16 cases of 47

XXY;10 of 46

XY/47

XXY and 8 of 46

XY.The results indicated that in the 47

XXY group and 46

XY/47

XXY group

their frequencies of Ag-NOR and Ag-AA were significantly higher than that in the normal’s 46

XY (p<0.001) . The frequency of the 47

XXY group was higher than that in 46

XY/47

XXY group (p<0.05). It may be related with the amount of the hormone and tracscriptive of rRNA genes on the acrocentric chromosome

关键词

Klinefelter综合征核仁形成区近端着丝粒染色体

Keywords

Klinefelter’s syndromeAcrocentric chromosomeNucleolus organizer region

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