QUANTITATIVE DETERMINATION OF RANITIDINE SUPPOSITORY BY UV SPECTROPHOTOMETRY METHOD USING THREE-WAVELENGTH

doi:10.13406/j.cnki.cyxb.1988.04.026

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QUANTITATIVE DETERMINATION OF RANITIDINE SUPPOSITORY BY UV SPECTROPHOTOMETRY METHOD USING THREE-WAVELENGTH

更新时间：2024-01-17

- QUANTITATIVE DETERMINATION OF RANITIDINE SUPPOSITORY BY UV SPECTROPHOTOMETRY METHOD USING THREE-WAVELENGTH
- Journal of Chongqing Medical University Issue 4, Pages: 314-317(1988)
- 作者机构：
  
  重庆医科大学检验系
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1988.04.026
  CLC：
- Published：1988，
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[1]严怡怡,袁泰先,叶运奎.三波长法测定雷尼替丁栓剂的含量[J].重庆医科大学学报,1988(04):314-317.

QUANTITATIVE DETERMINATION OF RANITIDINE SUPPOSITORY BY UV SPECTROPHOTOMETRY METHOD USING THREE-WAVELENGTH. [J]. Journal of Chongqing Medical University (4):314-317(1988)
[1]严怡怡,袁泰先,叶运奎.三波长法测定雷尼替丁栓剂的含量[J].重庆医科大学学报,1988(04):314-317. DOI： 10.13406/j.cnki.cyxb.1988.04.026.

QUANTITATIVE DETERMINATION OF RANITIDINE SUPPOSITORY BY UV SPECTROPHOTOMETRY METHOD USING THREE-WAVELENGTH. [J]. Journal of Chongqing Medical University (4):314-317(1988) DOI： 10.13406/j.cnki.cyxb.1988.04.026.

摘要

本文建立了H

—受体阻断剂雷尼替丁栓剂含量的紫外三波长测定法.样品不经处理

溶解后直接在305、312.4、360nm三个组合波长处测定雷尼替丁栓剂的含量

可完全消除杂质的干扰.方法回收率为98.5%—102.5%

CV%=1.28%（n=10）线性范围为5.0—200ug（r=0.9999）.本法快速、简便、准确、可用于雷尼替丁栓剂的质量控制及含量测定

Abstract

After disolved in distilled water

ranitidine ean be determined quantitatively at 305

312.4

360 nm by three-wavelength spectrophotometric method without pretreatment

the interferences of bases can be completely eliminated. The recovery of the present method is 98.5-102.5%

and the CV% is 1.28%(n=10). This is good linearity between the range 5.0-200.0ug (r=0.9999). The method is fast

simple

precise and easy to handle

thus it is suitable for the quality control and determination of ranitidine suppository

关键词

雷尼替丁栓剂紫外三波长

Keywords

ranitidineSuppositoryMulti-Wavelength Spectrophotometry

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Related Author

严怡怡

叶运奎

袁泰先

朱治本

陈萍

蒋夏

Related Institution

Dept. of Analytical Chemistry, Faculty of Lab Medicine

重庆医科大学第一医院临床药理研究室

重庆医科大学第一医院麻醉科

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