THE CLINICAL SIGNIFICANCE OF ACTIVATED COAGULATION TIME (ACT) MONITORING DURING EXTRACORPOREAL CIRCULATION

doi:10.13406/j.cnki.cyxb.1988.02.012

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THE CLINICAL SIGNIFICANCE OF ACTIVATED COAGULATION TIME (ACT) MONITORING DURING EXTRACORPOREAL CIRCULATION

更新时间：2024-01-17

- THE CLINICAL SIGNIFICANCE OF ACTIVATED COAGULATION TIME (ACT) MONITORING DURING EXTRACORPOREAL CIRCULATION
- Journal of Chongqing Medical University Issue 2, Pages: 126-128(1988)
- 作者机构：
  
  重庆医科大学第一医院
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1988.02.012
  CLC：
- Published：1988，
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[1]陈敦敏,张幼君,房秀生.体外循环中激活全血凝血时间(ACT)测定及其临床意义[J].重庆医科大学学报,1988(02):126-128+125.

THE CLINICAL SIGNIFICANCE OF ACTIVATED COAGULATION TIME (ACT) MONITORING DURING EXTRACORPOREAL CIRCULATION. [J]. Journal of Chongqing Medical University (2):126-128(1988)
[1]陈敦敏,张幼君,房秀生.体外循环中激活全血凝血时间(ACT)测定及其临床意义[J].重庆医科大学学报,1988(02):126-128+125. DOI： 10.13406/j.cnki.cyxb.1988.02.012.

THE CLINICAL SIGNIFICANCE OF ACTIVATED COAGULATION TIME (ACT) MONITORING DURING EXTRACORPOREAL CIRCULATION. [J]. Journal of Chongqing Medical University (2):126-128(1988) DOI： 10.13406/j.cnki.cyxb.1988.02.012.

摘要

本文在40例心内直视手术中对肝素和鱼精蛋白的应用和剂量进行研究.通过测定病人的激活全血凝血时间（ACT）画出肝素剂量反应曲线作为肝素给药和推算鱼精蛋白剂量的依据.实验证明:肝素剂量反应曲线是体外循环术中术后控制肝素和鱼精蛋白给药剂量的一项简单而可靠的方法.

Abstract

The adequacy of anticoagulation and the precision of portamine neutralization at the conclusion of extracortoreal circulation were studied in 40 patients undergoing open-heart surgery. These patients were monitored by means of activated coagulation time (ACT) to creat a dose-response curve

from which appropriate dose of heparin and portamine was ca-lculated and administered. This study proves that the dose-response curve is a simple and reliable predictor for adequate control of heparin and portamine administration during and after extracorporeal circulation. It is also valuable in the prevention of various pre-opera-tive and post-operative complications commonly encountered in our daily practice

关键词

激活全血凝血时间（ACT）体外循环肝素鱼精蛋白肝素剂量反应曲线

Keywords

activated coagulation time(ACT)Extracorporeal circulationheparinprota-minedoseresponse curve

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