Laboratory of Electron Microscopy Li Weixin Huang Chongben. ELECTRON MICROSCOPIC OBSERVATIONS OF HYPERTROPHIC SCAR OF HUMAN SKIN WITH THE APPLICATOR TREATMENT OF RADIOACTIVE NUCLIDE. [J]. Journal of Chongqing Medical University (2):91-93(1988)
Laboratory of Electron Microscopy Li Weixin Huang Chongben. ELECTRON MICROSCOPIC OBSERVATIONS OF HYPERTROPHIC SCAR OF HUMAN SKIN WITH THE APPLICATOR TREATMENT OF RADIOACTIVE NUCLIDE. [J]. Journal of Chongqing Medical University (2):91-93(1988) DOI: 10.13406/j.cnki.cyxb.1988.02.003.
ELECTRON MICROSCOPIC OBSERVATIONS OF HYPERTROPHIC SCAR OF HUMAN SKIN WITH THE APPLICATOR TREATMENT OF RADIOACTIVE NUCLIDE
摘要
本文报告3例以放射线核素(
32
P敷贴器或
90
Sr—
90
Y敷贴器)防治疤痕增殖的电镜观察.成纤维细胞呈现退变
主要是核的异染色质增多及核固缩
胞质内线粒体肿胀
粗面内质网扩大和出现一些含细丝状物质的颗粒或泡.
90
Sr—
90
Y敷贴器所致退变较
32
P敷贴器为重.结果提示成纤维细胞的合成与排泌功能受损
从而抑制疤痕增殖
Abstract
Three Patients with hypertrophic scars were treated by phosphorous 32 or strontium 90 applicator
and observed under the electron microscope. The main alterations in fibroblasts were heterochromatin increasing and pyknosis; mitochondrial swelling and dilatation of rough endoplasmic reticulum. In addition
some granules or vacuoles contained filament-like materials appearing in the cytoplasm. The degeneration of fibroblasts treated by strontium 90 applicator was more serious than that of phosphorous 32 applicator. These results suggest that the functions of synthesis and secretion of fibroblasts are damaged