OBSERVATIONS ON THE TREATMENT OF ADVANCED GASTRIC CANCER WITH TRANSFER FACTOR

doi:10.13406/j.cnki.cyxb.1987.04.003

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OBSERVATIONS ON THE TREATMENT OF ADVANCED GASTRIC CANCER WITH TRANSFER FACTOR

更新时间：2024-01-17

- OBSERVATIONS ON THE TREATMENT OF ADVANCED GASTRIC CANCER WITH TRANSFER FACTOR
- Journal of Chongqing Medical University Issue 4, Pages: 226-230(1987)
- 作者机构：
  
  1. 重庆医科大学第一医院外科教研室
  2. 重庆医科大学第一医院外科实验室
  3. 重庆医科大学第一医院外科教研室重庆医科大学第一医院外科实验室
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1987.04.003
  CLC：
- Published：1987，
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[1]时德,董浦江.转移因子治疗晚期胃癌的观察[J].重庆医科大学学报,1987(04):226-230.

OBSERVATIONS ON THE TREATMENT OF ADVANCED GASTRIC CANCER WITH TRANSFER FACTOR. [J]. Journal of Chongqing Medical University (4):226-230(1987)
[1]时德,董浦江.转移因子治疗晚期胃癌的观察[J].重庆医科大学学报,1987(04):226-230. DOI： 10.13406/j.cnki.cyxb.1987.04.003.

OBSERVATIONS ON THE TREATMENT OF ADVANCED GASTRIC CANCER WITH TRANSFER FACTOR. [J]. Journal of Chongqing Medical University (4):226-230(1987) DOI： 10.13406/j.cnki.cyxb.1987.04.003.

摘要

本文报告转移因子对19例晚期胃癌患者进行免疫治疗及临床观察

并随机抽样随访了同期术后未行免疫治疗的患者作为对照

结果显示转移因子确有增强细胞免疫功能的作用

可延长晚期胃癌的生存期。若用于早期胃癌或其他肿瘤的早期

配合手术、化疗或放疗估计会提高治疗效果。

Abstract

The effect of transfer factor(TF)on the treatment of advanced gastric cancer is reported in this paper. 19 cases were treated with TF and other 19 cases served as control. Therapy with TF in a dose of 2 units biw was instituted intramuscularly.24 months after operation

in the control group all patients died

while in the treated group

10 cases died and 9 survived(P<0.05). After 1 course of TF treatment( about 3 months after operation)

9 cases (75%) of the treated group turned positive (P<0.05) in PHA test

and 10 cases (90.9%) turned positive (P<0.05) in SD-SK test. In the control group

the tests remained unchanged.Percentage of E-rosette-forming cells (E-RFC) and lymphocyte transformation test(LTT) showed a significant increase after TF therapy. The average percentage of E-RFC increase from 44.3 + 8.2% to 71.4 + 9.7% (P<0.05) in 18 cases and that of LTT from 34

3+7.5% to 78.9 +6.4% (P<0.01) in 15 cases. In the control group there was no change.The preliminary results indicate that TF therapy is a valuable auzilliary means in the postoperative period of advanced gastric cancer for the improvement of general conditions and imm-unologic status of the patients

关键词

转移因子晚期胃癌治疗

Keywords

transfer factoradvanced gastric cancertherapy

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