PHA INDUCED RAT T-LYMPHOCYTE TRANSFOR MATION IN VIVO

doi:10.13406/j.cnki.cyxb.1987.02.002

您当前的位置：

首页 >

文章列表页 >

PHA INDUCED RAT T-LYMPHOCYTE TRANSFOR MATION IN VIVO

更新时间：2024-01-17

- PHA INDUCED RAT T-LYMPHOCYTE TRANSFOR MATION IN VIVO
- Journal of Chongqing Medical University Issue 2, Pages: 80-83(1987)
- 作者机构：
  
  重庆医科大学人工肝研究室
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.1987.02.002
  CLC：
- Published：1987，
扫描看全文
[1]李非,舒昌达,李宗明.植物血凝素(PHA)诱导大鼠体内淋巴细胞转化的探讨[J].重庆医科大学学报,1987(02):80-83.

PHA INDUCED RAT T-LYMPHOCYTE TRANSFOR MATION IN VIVO. [J]. Journal of Chongqing Medical University (2):80-83(1987)
[1]李非,舒昌达,李宗明.植物血凝素(PHA)诱导大鼠体内淋巴细胞转化的探讨[J].重庆医科大学学报,1987(02):80-83. DOI： 10.13406/j.cnki.cyxb.1987.02.002.

PHA INDUCED RAT T-LYMPHOCYTE TRANSFOR MATION IN VIVO. [J]. Journal of Chongqing Medical University (2):80-83(1987) DOI： 10.13406/j.cnki.cyxb.1987.02.002.

摘要

本文发现连续三次肌肉注射PHA可使大鼠外周血淋巴母细胞百分率明显升高。这一现象与PHA剂量有严格的量效关系并可被环磷酰胺完全抑制。但一次静脉注射PHA只能使淋巴结内淋巴母细胞百分率增加。我们认为大鼠淋巴细胞在体内对PHA的这种增殖反应可作为T淋巴细胞转化功能的指标

并将其用于观察血液灌流时大鼠T淋巴细胞功能的改变

Abstract

After three consecutive intramuscular doses of PHA

the percentage of lymphoblasts in the rat peripheral blood increased significantly by three times as that of those injected with normal saline. The response to PHA was strictly dose-dependent and could be totally suppressed by cyclophosphamide. But a single intravenous dose of PHA failed to increase the percentage of peripheral blood lymphoblasts in rats although the lymphatic tissue showed a similar response. This response could be regarded as an indicator of T-lymphocyte function in vivo

and therefore PHA-induced lymphocyte transformation in vivo may be a potential new method for detecting lymphocyte function

关键词

T淋巴细胞转化大鼠植物血凝素

Keywords

T-lymphocyte TransformationratPHA

references

Views

107

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Histopathological changes and pathological basis of the cryptorchidtestis in rats by maternal exposure to flutamide

DISPOSITION OF ~3H-PIPERAZINE FERULATE IN RATS

THE ALTERATIONS OF RENAL AND HEMODYNAMIC EFFECTS OF NATRIURETIC FACTOR IN ATRIA OF THE RATS WITH ACUTE HEART FAILURE

PRELIMINARY INVESTIGATION ON THE DETERMINATION OF β-ADRENOCEPTORS IN RAT UTERUS DURING OESTROUS CYCLE

THE MODEL OF MIDDLE CEREBRAL ARTERY OCCLUSION ON SPRAGUE-DAWIEY RAT

Related Author

Peng Jinpu

Zhang Deying

Cao Xining

Zhou Yue

Shen Lianju

Long Chunlan

He Dawei

Lin Tao

Related Institution

Department of Urology,the Children’s Hospital,Chongqing Medical University,Ministry of Education Key Laboratory of Child Development and Disorders,Key Laboratory of Pediatrics in Chongqing,Chongqing International Science and Technology Cooperation Center for Child Development and Disorders

重庆医科大学第一医院临床药理研究室

重庆医科大学基础医学部药理教研室

重庆医科大学病理生理学教研室

Department of Reproductive Physiology

⁰