Research progress of the characteristics of abnormal visual pathway and its clinical application in patients with Alzheimer's disease

Lianlian Wang; Feng Bai

doi:10.13406/j.cnki.cyxb.002905

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Research progress of the characteristics of abnormal visual pathway and its clinical application in patients with Alzheimer's disease

Correlation analysis of cognitive impairment and central biomarkers | 更新时间：2022-06-24

- Research progress of the characteristics of abnormal visual pathway and its clinical application in patients with Alzheimer's disease
- Journal of Shanxi Agricultural Sciences Vol. 46, Issue 11, Pages: 1388-1390(2021)
- 作者机构：
  
  1.江苏大学鼓楼临床医学院神经内科，南京　210008
  2.南京大学医学院附属鼓楼医院神经内科，南京　210008
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.002905
  CLC： R741
- Published：28 November 2021，
  
  Received：25 July 2021，
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Lianlian Wang, Feng Bai. Research progress of the characteristics of abnormal visual pathway and its clinical application in patients with Alzheimer's disease. [J]. Journal of Shanxi Agricultural Sciences 46(11):1388-1390(2021)
DOI：

Lianlian Wang, Feng Bai. Research progress of the characteristics of abnormal visual pathway and its clinical application in patients with Alzheimer's disease. [J]. Journal of Shanxi Agricultural Sciences 46(11):1388-1390(2021) DOI： 10.13406/j.cnki.cyxb.002905.

摘要

阿尔茨海默病（Alzheimer's disease，AD）是老年人中最常见的痴呆类型，表现为进展性、不可逆转的多维度认知功能障碍。视觉功能障碍是AD及其高风险人群轻度认知功能障碍（mild cognitive impairment，MCI）的认知损害特征之一，视觉环路功能障碍是其视觉症状的主要机制。利用神经影像学可以揭示AD谱系患者视觉环路的损害模式，有助于早期识别并干预AD的进展。本文将对AD谱系患者的视觉环路损害特征及其临床应用的研究进展进行综述。

Abstract

Alzheimer's disease (AD) is the most common form of dementia in the elderly who is characterized by progressive and irreversible loss of multidimensional cognitive function. Visual impairment is one of the features in AD and its high-risk population mild cognitive impairment (MCI) patients

and visual pathway dysfunction is associated with the underlying mechanism. Neuroimaging can reveal subtle changes in visual pathway in AD spectrum patients

which could help to early recognize and intervene in the progress of AD. In this article

we will review the progress of characteristics of abnormal visual pathway and its clinical application in AD spectrum patients.

关键词

阿尔茨海默病视觉环路神经影像学

Keywords

Alzheimer's diseasevisual pathwayneuroimaging

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