Study of gut microbiota dysbiosis induced depression and the underlying gut-brain mechanisms

doi:10.13406/j.cnki.cyxb.002888

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Study of gut microbiota dysbiosis induced depression and the underlying gut-brain mechanisms

更新时间：2024-01-09

- Study of gut microbiota dysbiosis induced depression and the underlying gut-brain mechanisms
- Journal of Chongqing Medical University Vol. 46, Issue 9, Pages: 1003-1007(2021)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.002888
  CLC： R749.4
- Published：2021，
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Study of gut microbiota dysbiosis induced depression and the underlying gut-brain mechanisms. [J]. Journal of Chongqing Medical University 46(9):1003-1007(2021)
DOI：

Study of gut microbiota dysbiosis induced depression and the underlying gut-brain mechanisms. [J]. Journal of Chongqing Medical University 46(9):1003-1007(2021) DOI： 10.13406/j.cnki.cyxb.002888.

摘要

抑郁症（major depressive disorder，MDD）是一种严重影响人类健康的重大精神疾病。越来越多的研究显示肠道微生物紊乱在MDD发病过程中具有重要调节作用。本课题组针对MDD存在的肠道微生物紊乱、引起MDD发病的关键肠道微生物、肠道微生物紊乱诱发MDD的肠-脑分子机制开展了系列研究，本文就课题组已取得的研究进展作一综述。

Abstract

Major depressive disorder (MDD) is a major mental disease which seriously affects human health. Increasing researches have shown that dysbiosis of gut microbiota plays an important role in the pathogenesis of MDD. We have carried out a series of researches to uncover the dysbiosis of gut microbiota in MDD and identify the key gut microflora that cause MDD

as well as the underlying molecular mechanisms. The present manuscript summarizes the research findings of our research group.

关键词

抑郁症肠道微生物肠-脑轴

Keywords

major depressive disordergut microbiotagutbrain axis

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Related Author

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Related Institution

Center for Reproductive Medicine,The First Affiliated Hospital of Chongqing Medical University

Department of Obstetrics and Gynecology,The Second People's Hospital of Banan District

Department of Endocrinology，The Children's Hospital，Zhejiang University School of Medicine，National Clinical Research Center for Child Health

Department of Psychiatry,the First Affiliated Hospital,Chongqing Medical University

重庆医科大学神经科学研究中心

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