Objective:To explore the appilication of health care communication APP in patients who received invasive mechanical ventilation. Methods:Totally patients who admitted into ICU from March 2016 to June 2016 were enrolled in the study. They were randomly divided into groups:experimental group and control group. Health care communication APP was used to communication with patients in experimental group while traditional method used to communication with patients in control group. General condition of the two group were record. Level of difficulty to communicate

scale of anxiety and depression and incidence of ICU delirium were compared between the two groups. Results:No statistical difference was noted in general condition

acute physiology and chronic health evalation Ⅱ（APACHE Ⅱ）between two groups（all P>0.05）. Statistical difference was noted in level of difficulty to communicate

scale of anxiety and depression and incidence of ICU delirium between two groups（all P<0.05）. Conclusion:Health care communication APP has obvious advantages in reducing level of difficulty to communicate

reducing incidence of anxiety and depression and delirium. So

it has good application prospect.