Objective:To evaluate the relationship between the levels of 25-hydroxyvitamin D[25（OH）D]

parathyroid hormone（PTH）and incidence of hypertension by dose response Meta-analysis

respectively. Methods:Databases including Pub Med

Embase

CBM

CNKI and VIP were searched for prospective studies on the relationship between the levels of 25（OH）D

PTH and incidence of hypertension up to August 2016. The relationship between the levels of 25（OH）D

PTH and incidence of hypertension was assessed by dose response model

and a general analysis was conducted by using Stata 13.0 software. Results:Eight studies involving 25 658 participation which are from western countries were included. Linear dose response Meta-analysis indicated that by 25 nmol/L 25（OH）D and15 pg/m L PTH elevation

the risk of hypertension incidence would decrease 7%（RR=0.93

95%CI=0.89 to 0.97

P=0.000）and increase 6%（RR=1.06

95%CI=1.02 to 1.10

P=0.001）

respectively. Conclusion:The risk of hypertension showed a rising trend with the decrease in 25（OH）D concentrations and increase in PTH concentrations among the westerners

respectively. This provides information for the prevention of hypertension among the Asians.