Attention on the evaluation and treatment of depression in Parkinson’s disease

Su Wen; Chen Haibo

doi:10.13406/j.cnki.cyxb.001276

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Attention on the evaluation and treatment of depression in Parkinson’s disease

更新时间：2024-01-17

- Attention on the evaluation and treatment of depression in Parkinson’s disease
- Journal of Chongqing Medical University Vol. 42, Issue 6, Pages: 648-650(2017)
- 作者机构：
  
  北京医院国家老年医学中心神经内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001276
  CLC： R749.4;R742.5
- Published：2017，
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Su Wen, Chen Haibo. Attention on the evaluation and treatment of depression in Parkinson’s disease. [J]. Journal of Chongqing Medical University 42(6):648-650(2017)
DOI：

Su Wen, Chen Haibo. Attention on the evaluation and treatment of depression in Parkinson’s disease. [J]. Journal of Chongqing Medical University 42(6):648-650(2017) DOI： 10.13406/j.cnki.cyxb.001276.

摘要

抑郁是帕金森病(Parkinson’s disease

PD)常见的非运动症状之一

由于往往与PD的运动症状及其他神经精神症状并发

临床上对其正确评估仍存在一定问题

因此

选择有效的、适合PD抑郁的评估量表至关重要。汉密尔顿抑郁量表、Beck抑郁量表、蒙哥马利抑郁量表、老年抑郁量表、康奈尔痴呆抑郁量表等可以有效地评价不同临床类型的PD抑郁。而且

不同临床类型的PD抑郁可能需要选择不同的治疗方法。其中

心理行为治疗有效

但在神经科容易被忽视。由于副作用较少

口服抗抑郁药仍然是最常用的手段

而剂末抑郁可通过调整多巴胺能药物得到改善。重复经颅磁刺激以及脑深部电刺激术等方法尚需更多临床对照研究验证。进一步提高PD抑郁的识别

开发更为有效的治疗方法

对帮助改善患者的生活质量至关重要。

Abstract

Depression is one of most common non-motor symptoms in Parkinson’s disease（PD）. Due to the overlap of somatic symptoms and other neuropsychiatric manifestations

assessing the depression of PD is still a challenge in clinical practice. It is of great importance to choose a valid and appropriate depression scale to detect it. Hamilton depression scale

Beck depression inventory

Montgomery-Asberg depression rating scale

geriatric depression scale

Cornell scale for depression in dementia can effectively evaluate different clinical types of depression in PD. Moreover

different clinical types of depression may need to choose different treatments. Among them

the cognitive behavioral therapy is effective

but easy to be ignored by the neurologist. With fewer side effects

oral antidepressant drugs are still the most commonly used

and depression in the "off"period can be improved by adjusting the dopaminergic drugs.The efficacy of repetitive transcranial magnetic stimulation and deep brain stimulation method still needs more controlled clinical study to be verified. Further improving the recognition to the depression of PD and developing more effective treatments

is crucial to help improve the patient’s quality of life.

关键词

帕金森病抑郁评估治疗

Keywords

Parkinson’s diseasedepressionevaluationtreatment

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Related Institution

Department of Endocrinology，The First Hospital of China Medical University，Institute of Endocrinology of China Medical University，Key Laboratory of Thyroid Diseases ofNational Health Commission of the People’s Republic of China

Department of Traditional Chinese Medicine，Children’s Hospital，Zhejiang University School of Medicine/ National Clinical Research Center for Child Health

Department of Pediatrics，The Affiliated Hospital of Nanjing University of Chinese Medicine，The First Clinical Medical College of Nanjing University of Chinese Medicine

Department of Respiratory Medicine，Children’s Hospital，Zhejiang University School of Medicine/ National Clinical Research Center for Child Health

Department of Urology，The Second Affiliated Hospital of Chongqing Medical University, The Second Affiliated Hospital of Chongqing Medical University

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