Recent progress in semantic dementia

Guo Qihao; Chen Keliang

doi:10.13406/j.cnki.cyxb.001274

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Recent progress in semantic dementia

更新时间：2024-01-17

- Recent progress in semantic dementia
- Journal of Chongqing Medical University Vol. 42, Issue 6, Pages: 634-637(2017)
- 作者机构：
  
  复旦大学附属华山医院神经内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001274
  CLC： R749.1
- Published：2017，
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Guo Qihao, Chen Keliang. Recent progress in semantic dementia. [J]. Journal of Chongqing Medical University 42(6):634-637(2017)
DOI：

Guo Qihao, Chen Keliang. Recent progress in semantic dementia. [J]. Journal of Chongqing Medical University 42(6):634-637(2017) DOI： 10.13406/j.cnki.cyxb.001274.

摘要

语义性痴呆属于额颞叶变性的一种重要亚型

典型症状包括命名障碍和词语理解障碍

但复述、自发语言等相对完好。神经影像学检查可见以颞叶为主的双侧半球不对称脑萎缩

并存在广泛的功能和结构连接的受损。由于语义性痴呆患者具有自发的、特征性的语义功能损害

它一直是语义记忆的神经机制研究的重要疾病模型。

Abstract

Semantic dementia（SD）

one of the main variants of frontotemporal lobar degeneration

presents specific language disturbances with impaired naming and word comprehension but a fluent and grammatically correct speech. Patients with SD show bilateral

though typically asymmetrical

atrophy of the anterior temporal lobe

and widespread damage of brain functional and anatomical connectivity. Because SD is characterized by a gradual and modality-independent loss of semantic knowledge

it is considered important disease model of the neural mechanism research of semantic memory.

关键词

语义性痴呆额颞叶变性命名障碍

Keywords

semantic dementiafrontotemporal lobar degenerationanomia

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Related Institution

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Department of Neurology, The Second Hospital of HeBei Medical University

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