Precision treatment in Parkinson’s disease

Shang Huifang; Chen Yongping

doi:10.13406/j.cnki.cyxb.001272

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Precision treatment in Parkinson’s disease

更新时间：2024-01-17

- Precision treatment in Parkinson’s disease
- Journal of Chongqing Medical University Vol. 42, Issue 6, Pages: 651-654(2017)
- 作者机构：
  
  四川大学华西医院神经内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001272
  CLC： R742.5
- Published：2017，
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Shang Huifang, Chen Yongping. Precision treatment in Parkinson’s disease. [J]. Journal of Chongqing Medical University 42(6):651-654(2017)
DOI：

Shang Huifang, Chen Yongping. Precision treatment in Parkinson’s disease. [J]. Journal of Chongqing Medical University 42(6):651-654(2017) DOI： 10.13406/j.cnki.cyxb.001272.

摘要

精准医学是生物医学信息与大数据科学交叉发展起来的新医学概念和医学模式。精准医学应用现代遗传技术、分子影像技术、生物信息技术

结合患者生活环境和临床数据

实现精准疾病分类及诊断

制定具有个性化的疾病预防和治疗方案。帕金森病作为一种复杂的

表型多样、遗传异质性大

环境与遗传因素共同作用的神经变性疾病

因此针对帕金森病患者的个体化治疗尤为重要。本文结合近期的研究成果与学者观点

阐述通过精准医学对帕金森病的研究提供新的治疗思路和方法。

Abstract

Precision medicine is the new medicine concept and medical model

emerging from the combination of biomedical informatics and big data science. Genetics

molecular imaging

bioinformatics and management provide tools to realize the idea of precision medicine. The goal of precision medicine is to deliver optimally targeted and timed interventions tailored to an individual’s molecular drivers of disease. Parkinson’s disease

the second most common neurodegenerative disease

is characterized by complex

phenotypic diversity and genetic heterogeneity

interaction of environmental and genetic factors

therefore

individualized treatment in Parkinson’s disease is very important. In the current work

by integrating data reported in recent literature

we described the current practice of precision medicine in Parkinson’s disease

especially in precision treatment.

关键词

帕金森病表型多样性遗传异质性精准治疗

Keywords

Parkinson’s diseasephenotypic diversitygenetic heterogeneityprecision treatment

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Related Institution

Department of Neurology,the First Affiliated Hospital of Nanjing Medical University,Jiangsu Province People’s Hospital

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Department of Neurology,Beijing Hospital,National Center of Gerontology

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