Advance of magnetic resonance imaging of Parkinson’s disease

Jin Lirong; Huang Zhen

doi:10.13406/j.cnki.cyxb.001271

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Advance of magnetic resonance imaging of Parkinson’s disease

更新时间：2024-01-17

- Advance of magnetic resonance imaging of Parkinson’s disease
- Journal of Chongqing Medical University Vol. 42, Issue 6, Pages: 662-666(2017)
- 作者机构：
  
  复旦大学附属中山医院神经内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001271
  CLC： R742.5
- Published：2017，
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Jin Lirong, Huang Zhen. Advance of magnetic resonance imaging of Parkinson’s disease. [J]. Journal of Chongqing Medical University 42(6):662-666(2017)
DOI：

Jin Lirong, Huang Zhen. Advance of magnetic resonance imaging of Parkinson’s disease. [J]. Journal of Chongqing Medical University 42(6):662-666(2017) DOI： 10.13406/j.cnki.cyxb.001271.

摘要

帕金森病(Parkinson’s disease

PD)是常见的中枢神经系统退行性疾病。发现并研究PD的神经影像学标志物有助于早期诊断、评估疾病状态。随着结构和功能磁共振技术的飞速发展

现有的磁共振序列可检测到PD患者脑内铁过度沉积、弥散异常、血流灌注改变、神经黑色素含量减少、结构和功能连接异常等病理改变。本文将就PD患者不同受累部位及相应的磁共振检测技术进展做一综述。

Abstract

Parkinson’s disease（PD）is a common neurodegenerative disorder. Discovering and studying the neuroimaging markers of PD helps to diagnose

or assess state of the disease. With the rapid development of structural and functional magnetic resonance imaging（MRI）technology

the existing MRI sequences can detect pathological changes of PD patients

including excessive iron deposition

abnormal water diffusion

blood perfusion changes

decreased neuromelanincontent and structural or functional abnormalities.This article will review current state and progress of MRI technology to detect different parts of brain of PD patients.

关键词

帕金森病磁共振综述

Keywords

Parkinson’s diseasemagnetic resonance imagingreview

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Related Institution

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