Introduction to the recent international diagnostic criteria for Alzheimer’s disease

Liang Bin; Yuan Fang

doi:10.13406/j.cnki.cyxb.001266

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Introduction to the recent international diagnostic criteria for Alzheimer’s disease

更新时间：2024-01-17

- Introduction to the recent international diagnostic criteria for Alzheimer’s disease
- Journal of Chongqing Medical University Vol. 42, Issue 6, Pages: 682-683(2017)
- 作者机构：
  
  1. 山东大学齐鲁医院神经内科
  2. 山东大学齐鲁医院(青岛)保健科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001266
  CLC： R749.16
- Published：2017，
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Liang Bin, Yuan Fang. Introduction to the recent international diagnostic criteria for Alzheimer’s disease. [J]. Journal of Chongqing Medical University 42(6):682-683(2017)
DOI：

Liang Bin, Yuan Fang. Introduction to the recent international diagnostic criteria for Alzheimer’s disease. [J]. Journal of Chongqing Medical University 42(6):682-683(2017) DOI： 10.13406/j.cnki.cyxb.001266.

摘要

国际上新近的较权威的诊断标准有:2011年美国国家衰老研究所和阿尔茨海默病学会(the National Institute on Aging-Alzheimer’s Association

NIA-AA)发布的新诊断指南以及2014年国际工作组(IWG)推出的新版阿尔茨海默病(Alzheimer’s disease

AD)科研诊断标准(IWG-2)。两个诊断标准都认为AD是一个连续的过程

其诊断标准能覆盖AD的全程

即从无症状期到疾病的终末期

所以两者有很多共同点

比如认可生物标记物于诊断流程中的作用

也都认同病程中存在生物标志物阳性但临床无症状的阶段。但两者的AD痴呆诊断标准侧重点和细节不同

也各有其局限性和随着认知领域快速发展而实时更新的必要性。

Abstract

The recent authoritative international diagnostic criteria included the National Institute on Aging-Alzheimer’s Association（NIA-AA）diagnostics criterion published in 2011 and a new AD research diagnostic criterion（IWG-2）in 2014 launched by the International Working Group（IWG）. Both the two diagnostic criteria considered that AD was a continuous process

and the diagnostic criteria could be covered in the whole process of the Alzheimer’s disease from asymptomatic period to the late disease. So both the two diagnostic criteria had a lot in common

such as the recognition of the role of biomarkers in the diagnosis process

the existence of clinically asymptomatic stage while the biomarkers in positive. But the focus and details of the AD dementia diagnostic criteria are different in the two diagnostic criteria

and each had its own limitations and the need to update it in real time with the rapid development of the cognitive field.

关键词

阿尔茨海默病诊断标准生物标志物

Keywords

Alzheimer’s diseasediagnostic criteriabiomarkers

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