Analysis of weight change and its related factors of Parkinson’s disease patients

Ma Chengxiao; Yuan Yongsheng; Zhang Jiejin; Ding Jian; Zhang Kezhong

doi:10.13406/j.cnki.cyxb.001264

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Analysis of weight change and its related factors of Parkinson’s disease patients

更新时间：2024-01-17

- Analysis of weight change and its related factors of Parkinson’s disease patients
- Journal of Chongqing Medical University Vol. 42, Issue 6, Pages: 719-723(2017)
- 作者机构：
  
  1. 南京医科大学
  2. 南京医科大学第一附属临床学院江苏省人民医院神经内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001264
  CLC： R742.5
- Published：2017，
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Ma Chengxiao, Yuan Yongsheng, Zhang Jiejin, et al. Analysis of weight change and its related factors of Parkinson’s disease patients. [J]. Journal of Chongqing Medical University 42(6):719-723(2017)
DOI：

Ma Chengxiao, Yuan Yongsheng, Zhang Jiejin, et al. Analysis of weight change and its related factors of Parkinson’s disease patients. [J]. Journal of Chongqing Medical University 42(6):719-723(2017) DOI： 10.13406/j.cnki.cyxb.001264.

摘要

目的:研究帕金森病(Parkinson’s disease

PD)患者体质量变化及相关影响因素。方法:自2015年1月至2015年10月

选取江苏省人民医院PD专病门诊共122名PD患者应用体质量测量仪、统一帕金森病评分量表(unified Parkinson’s disease rating scale

UPDRS)、Hoehn-Yahr分级(H-Y分级)、PD生活质量问卷调查(Parkinson’s disease questionnaire

PDQ-39)以及PD非运动症状评估量表(non-motor symptoms score

NMSS)

评估PD患者体质量变化及相关影响因素

以同时期门诊健康体检人员共100例作为对照

对研究数据采取独立样本的t检验及多元线性回归分析。结果:PD患者人体质指数(body mass index

BMI)较正常人群有明显的下降(t=3.999

P=0.000)

且以脂肪量丢失为主;女性PD患者出现体质量丢失的风险更高;H-Y分级≥2.5的PD患者体质量下降更加明显。结论:PD病人的BMI较健康对照人群有明显的下降

女性PD患者有更高的风险出现体质量丢失;PD患者中H-Y分级≥2.5的人群更易出现体质量丢失。

Abstract

Objective:To study the changes in body weight and related factors of Parkinson’s disease（PD）patients. Methods:One hundred and twenty-two PD patients

selected from PD Special Disease Clinic of Jiangsu Province People’s Hospital from January 2015 to October 2015

were measured by weight measuring instrument

unified Parkinson disease rate scale（UPDRS）

Hoehn-Yahr grading（H-Y）

Parkinson disease questionnaire（PDQ-39）and non-motor symptoms score（NMSS）to assess weight changes and related clinical data. A total of 100 cases outpatient medical personnel of the same period were chosen as control. Independent samples t test

and multiple linear regression analysis of data were used. Results:Body mass index（BMI）of PD patients had a significant decline compared with that of healthy adults（t=3.999

P=0.000）

mainly in fat loss.Female PD patients had a higher risk of weight loss. H-Y≥2.5 PD patients had more obvious weight loss. Conclusion:BMI reduces more evidently in PD patients than in controls. Female PD patients have a higher risk of weight loss. PD patients with H-Y≥2.5 are more prone to weight loss.

关键词

帕金森病体质指数H-Y分级性别身体脂肪率

Keywords

Parkinson’s diseasebody mass indexHoehn-Yahr gradinggenderbody fat rate

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