Growth hormone and anisodamine in the treatment of intrauterine re-adhesion after transcervical resection

Yang Jinjin; Meng Yuejin

doi:10.13406/j.cnki.cyxb.001239

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Growth hormone and anisodamine in the treatment of intrauterine re-adhesion after transcervical resection

更新时间：2024-01-17

- Growth hormone and anisodamine in the treatment of intrauterine re-adhesion after transcervical resection
- Journal of Chongqing Medical University Vol. 42, Issue 4, Pages: 437-440(2017)
- 作者机构：
  
  河南科技大学第一附属医院妇产科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001239
  CLC： R713.4
- Published：2017，
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Yang Jinjin, Meng Yuejin. Growth hormone and anisodamine in the treatment of intrauterine re-adhesion after transcervical resection. [J]. Journal of Chongqing Medical University 42(4):437-440(2017)
DOI：

Yang Jinjin, Meng Yuejin. Growth hormone and anisodamine in the treatment of intrauterine re-adhesion after transcervical resection. [J]. Journal of Chongqing Medical University 42(4):437-440(2017) DOI： 10.13406/j.cnki.cyxb.001239.

摘要

目的:探讨生长激素、山莨菪碱预防宫腔粘连分离术后再粘连的临床价值。方法:选取成功行宫腔镜下宫腔粘连分离术的中重度宫腔粘连患者65例

根据术后是否联合应用生长激素、山莨菪碱

将研究对象分成对照组(n=22)、生长激素(growth hormone

GH)组(n=18)、GH+654-2组(n=25)

对照组术后采取常规的综合治疗方法;GH组在对照组的基础上

联合皮下注射生长激素;GH+654-2组在GH组的基础上

术后口服山莨菪碱。术后3个月

比较3组患者的宫腔再粘连率、月经改善情况及月经周期同一时间的子宫内膜厚度。结果:比较3组患者的术前宫腔粘连程度、月经情况及子宫内膜厚度

差异均无统计学意义(均P>0.05);术后对照组、GH组、GH+654-2组的子宫内膜厚度分别为:(5.18±0.21)、(5.94±0.27)、(5.72±0.26)mm;月经改善率分别为:68.2%、88.9%、96.0%;GH组、GH+654-2组的子宫内膜厚度及月经改善率均优于对照组

差异有统计学意义(P<0.05)

但GH组与GH+654-2组比较

差异无统计学意义(P>0.05);对照组的宫腔再粘连率(31.8%)高于GH组(27.8%)与GH+654-2组(24.0%)

但3组间差异无统计学意义(P>0.05)。结论:生长激素、山莨菪碱联合以往的综合辅助治疗方法

能够增加宫腔粘连分离术后的子宫内膜厚度

有利于月经的恢复

对临床疗效的提高具有积极意义。

Abstract

Objective:To explore the clinical value of the growth hormone and anisodamine in the treatment of intrauterine re-adhesion after transcervical resection. Methods:Clinical data of 65 patients who were diagnosed with moderate or severe intrauterine adhesions and underwent transcervical resection of adhesions were analyzed retrospectively. According to the different treatment methods after operation

patients were divided into three groups:22 cases in the control group

18 cases in the GH group

25 cases in GH +654-2 group. Control group was treated by conventional therapy. GH group was treated with subcutaneous injection of growth hormone on the basis of the control group. GH+654-2 group was treated with oral anisodamine in the postoperative on the basis of the GH group. Three months after operation

intrauterine re-adhesion rate

menstrual improvement and endometrial thickness in the same time of menstrual cycle were compared among three groups. Results:There was no significant differences in the degree of intrauterine adhesion

menstruation and endometrial thickness of three groups before operation（P>0.05）. After the operation

endometrial thicknesses of the control group

GH group

GH+654-2 group were（5.18±0.21）

（5.94±0.27）

（5.72±0.26）mm and menstrual improvement rates were:68.2%

88.9%

96%. GH group and GH+654-2 group were significantly better than the control group in the increase of endometrial thickness and menstrual volume

with statistically significant differences（P<0.05）

but there was no significant difference between t he GH group and the GH+654-2 group（P>0.05）. The recurrent rate of control group（31.8%）was higher than that of GH group（27.8%）and GH+654-2 group（24.0%）

but there was no significant difference between the three groups（P>0.05）. Conclusion:Growth hormone and anisodamine combined with previous comprehensive adjuvant therapy can increase the endometrial thickness after TCRA and is conducive to the recovery of menstruation

having positive significance in the improvement of clinical curative effect.

关键词

宫腔粘连宫腔粘连分离术生长激素山莨菪碱

Keywords

intrauterine adhesiontranscervical resection of adhesiongrowth hormoneanisodamine

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