Analysis of the effect of readhesion of Combined application of chitosan and balloon stent in the prevention of severe intrauterine adhesions

Xiao Tianhui; Le Aiwen; Zhuo Rong; Tao Yu; Wang Zhonghai

doi:10.13406/j.cnki.cyxb.001238

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Analysis of the effect of readhesion of Combined application of chitosan and balloon stent in the prevention of severe intrauterine adhesions

更新时间：2024-01-17

- Analysis of the effect of readhesion of Combined application of chitosan and balloon stent in the prevention of severe intrauterine adhesions
- Journal of Chongqing Medical University Vol. 42, Issue 4, Pages: 433-436(2017)
- 作者机构：
  
  广东医科大学附属深圳南山临床学院妇科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001238
  CLC： R713.4
- Published：2017，
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Xiao Tianhui, Le Aiwen, Zhuo Rong, et al. Analysis of the effect of readhesion of Combined application of chitosan and balloon stent in the prevention of severe intrauterine adhesions. [J]. Journal of Chongqing Medical University 42(4):433-436(2017)
DOI：

Xiao Tianhui, Le Aiwen, Zhuo Rong, et al. Analysis of the effect of readhesion of Combined application of chitosan and balloon stent in the prevention of severe intrauterine adhesions. [J]. Journal of Chongqing Medical University 42(4):433-436(2017) DOI： 10.13406/j.cnki.cyxb.001238.

摘要

目的:探讨宫腔粘连电切术后3种方法预防术后再粘连的疗效。方法:91例重度宫腔粘连患者

根据术后处理方法随机分成3组

91例患者均行B超监护下宫腔镜下宫腔粘连电切术

A组术后放置宫内节育器+口服戊酸雌二醇。B组术后放置几丁糖+宫内节育器+口服戊酸雌二醇。C组术后放置几丁糖+COOK球囊支架+口服戊酸雌二醇。术后3个月评估月经改善情况

并行二次宫腔镜检查评估宫腔粘连改善情况。结果:从宫腔粘连及月经改善情况两个维度进行比较

C组有效率高于B组

B组有效率高于A组

C组有效率高于A组

宫腔粘连改善总有效率方差分析（F=3.612

P=0.032）

月经改善总有效率秩和检验比较（χ

=8.984

P=0.029）。组间比较差异有统计学意义。结论:TCRA术后联合应用几丁糖、球囊支架可更加有效地预防重度宫腔粘连术后再粘连的发生。

Abstract

Objective:To investigate the effect of 3 methods of postoperative adhesion in patients with severeintrauterine adhesions.Methods:91 cases of severe intrauterine adhesions in patients

according to the operation method of postprocessing were randomly divided into 3 groups

91 patients underwent hysteroscopy under B-ultrasound monitoring uterine cavity adhesion electrocision. Group A after IUD + oral estradiol valerate. Group B after placement of chitosan + intrauterine device + oral estradiol valerate. Group C was placed with chitosan +COOK balloon stent + oral estradiol valerate. 3 months after the evaluation period to improve the situation

parallel two hysteroscopy to assess the improvement of uterine cavity adhesion. Results:From two dimensions of intrauterine adhesions and menstrual improvement

the total effective rate of group C was higher than that of group B

the total effective rate of group B was higher than that of group A

the total effective rate of group C was higher than that of group A. intrauterine adhesions total effective rate used variance analysis（F=3.612

P=0.032）;Menstruation to improve total effective comparison used rank sum test（χ

=8.984

P=0.029）.The difference was statistically significant（P

0.05）. Conclusion:The combined application of chitosan and balloon stent can prevent the recurrence of severe intrauterine adhesion after TCRA operation.

关键词

宫腔粘连宫内节育器几丁糖COOK球囊支架戊酸雌二醇

Keywords

intrauterine adhesionintrauterine devicechitosanCOOK balloon stentestradiol valerate

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