Efficacy of interceed absorbable adhesion barrier in prevention of intrauterine adhesions after hysteroscopic surgery

Yang Xiaozhuo; Meng Yuejin; Gu Xiaoli

doi:10.13406/j.cnki.cyxb.001233

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Efficacy of interceed absorbable adhesion barrier in prevention of intrauterine adhesions after hysteroscopic surgery

更新时间：2024-01-17

- Efficacy of interceed absorbable adhesion barrier in prevention of intrauterine adhesions after hysteroscopic surgery
- Journal of Chongqing Medical University Vol. 42, Issue 4, Pages: 441-445(2017)
- 作者机构：
  
  郑州大学第二附属医院妇产科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001233
  CLC： R713.4
- Published：2017，
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Yang Xiaozhuo, Meng Yuejin, Gu Xiaoli. Efficacy of interceed absorbable adhesion barrier in prevention of intrauterine adhesions after hysteroscopic surgery. [J]. Journal of Chongqing Medical University 42(4):441-445(2017)
DOI：

Yang Xiaozhuo, Meng Yuejin, Gu Xiaoli. Efficacy of interceed absorbable adhesion barrier in prevention of intrauterine adhesions after hysteroscopic surgery. [J]. Journal of Chongqing Medical University 42(4):441-445(2017) DOI： 10.13406/j.cnki.cyxb.001233.

摘要

目的:评价宫内放置防粘连膜(Interceed)在预防中重度宫腔粘连术后再粘连中的疗效。方法:收集2015年6月至2016年6月于郑州大学第二附属医院经宫腔镜检查诊断为中重度宫腔粘连并成功手术分离粘连的72例患者

随机分成2组

A组40例为Interceed组(TCRA宫腔粘连分离术术后宫内放置防粘连膜预防粘连)

B组32例为几丁糖组(TCRA宫腔粘连分离术术后宫内灌注医用几丁糖3 m L预防粘连)

2组均行TCRA+E2V+生长激素综合治疗。随访术后1个月、3个月2组宫腔再粘连情况及术后3个月子宫内膜生长情况。结果:Interceed组术后1个月总有效率(77.5%)及术后3个月总有效率(87.5%)均明显高于几丁糖组术后1个月总有效率(53.1%)及术后3个月总有效率(56.3%)

差异具有统计学意义(P<0.05)

Interceed组术后3个月内膜生长厚度[(6.38±2.70)mm]明显高于几丁糖组术后3个月内膜生长厚度[(4.97±1.60)mm]

差异有统计学意义(P<0.05)。结论:Interceed有效预防中重度宫腔粘连术后宫腔再粘连的发生

临床价值高。

Abstract

Objective:To evaluate the efficacy of interceed absorbable adhesion barrier in the prevention of intrauterine adhesions after hysteroscope operation among patients with moderate to severe intrauterine adhesions. Methods :Totally 72 cases of moderate to severe intrauterine adhesions from June 2015 to June 2016 in the Second Affiliated Hospital of Zhengzhou University were collected

and they were divided into two groups:interceed group（40 cases） and chitosan group（32 cases）. Patients of interceed group were treated with TCRA+E2V+GH+interceed absorbable adhesion barrier

while patients of chitosan group were treated with TCRA+E2V+GH+chitosan. Patients of two groups were followed up to understand uterine recovery after 1 and 3 months and endometrial recovery after 6 months. Results:The effective rate of interceed group after 1 and 3 months was remarkably higher than that of the chitosan group

with statistically significant differences（P<0.05）. The thickness of endometrium after 3 months in the interceed group was thicker than that in the chitosan group

with statistically significant differences（P<0.05）. Conclusion:Interceed absorbable adhesion barrier is effective in the treatment of moderate to severe intrauterine adhesions.

关键词

宫腔粘连防粘连膜几丁糖生长激素

Keywords

intrauterine adhesionsinterceed absoubable adhesion barrierchitosangrowth hormone

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