Objective:To evaluate the feasibility of dexmedetomidine in the anesthesia for bronchial foreign body removal and to explore the influence of dexmedetomidine on the circulatory and respiratory function in pediatric patients. Methods:Eighty participants were recruited from July 2013 to November 2015 and were divided randomly into 2 groups（n=40）:the dexmedetomidine group（group D）and control group（group C）. The anesthesia induction was performed with sevoflurane on all participants. The anesthesia maintenance in the group D was performed with intravenous administration of dexmedetomidine and remifentanil;the anesthesia maintenance in the group C was performed with intravenous administration of propofol and remifentanil. The administration of anesthetics stopped just after the surgery completion. The heart rate（HR）

mean arterial pressure（MAP）

respiration rate was recorded at the following time points:before anesthesia induction（T0）

inserting laryngoscope（T1）

inserting bronchoscope（T2）

5min after bronchoscope insertion（T3）

withdraw bronchoscope（T4）

5min after bronchoscope withdraw（T5）

PACU dicharge（T6）. Results:Compared with those of T0

the reduction of HR

MAP

RR at T1-T4 in group D was milder in group C（P<0.01）. No difference was found in neither the anesthesia duration and surgery duration[（22.35±4.50）min vs.（22.43±4.70）min]

but the recovery time in group D increased as compared with that in group C（21[16

25] min vs 13[11

15] min

P<0.01）;the incidence of intraoperative respiratory depression and hypoxemia was lower in group D（3/40

1/40） than in group C（12/40

7/40）（P <0.01）. Conclusion:In pediatric patients undergoing bronchial foreign body removal

as compared with propofol

dexmedetomidine inhibits the circulatory and respiratory function mildly and results in less respiratory depression and hypoxemia

yet it might prolong the recovery time after anesthesia.