Wang Jiali, Yao Yunqing, Zhang Fenglian, et al. Carotid artery calcification and its relative factors in patients with maintenance peritoneal dialysis. [J]. Journal of Chongqing Medical University 42(2):232-235(2017)
DOI:
Wang Jiali, Yao Yunqing, Zhang Fenglian, et al. Carotid artery calcification and its relative factors in patients with maintenance peritoneal dialysis. [J]. Journal of Chongqing Medical University 42(2):232-235(2017) DOI: 10.13406/j.cnki.cyxb.001147.
Carotid artery calcification and its relative factors in patients with maintenance peritoneal dialysis
Objective:To discuss the relative factors of carotid calcification in maintenance peritoneal dialysis patients. Methods:One hundred patients with maintenance peritoneal dialysis in the Central Hospital of Mianyang were involved and divided into carotid artery calcification group(55 cases)and the normal group(45 cases)according to whether having carotid artery calcification. Their general dialysis data were collected for the evaluation of dialysis adequacy and residual renal function. The calcification of carotid arteries was assessed by the color Doppler ultrasonography. The independent risk factors for carotid artery thickening and calcification were analyzed by binary logistic regression analysis. Results:Compared with those of normal group
the age(42.36±8.79 vs. 34.93±9.60)years
fasting blood glucose(6.91±0.44 vs. 6.66±0.30)mmol/L
calcium and phosphorus product(3.98±0.40 vs. 3.82±0.30)mmol/L
parathyroid hormone(270.72±30.24 vs. 260.23±11.05)ng/L in the carotid artery calcification group were increased(P
<
0.05)
while the residual renal function(2.25±0.74 vs. 5.14±1.07)m L/min
total creatinine clearance rate(Ccr)(59.92±3.94 vs. 66.11±7.01)L/(week·1.73 m
2
)
residual kidney Ccr(19.66±2.85 vs. 25.07±6.53)L/(week·1.73 m
residual kidney Kt/V(1.12±0.30 vs. 1.45±0.28)were decreased. Logistic regression analysis showed that dialysis age(OR=1.218
P=0.039)
the calcium-phosphorus product(OR=70.403
P=0.037)
the residual renal function(OR=0.030
P=0.001)and the residual kidney Ccr(OR=0.692
P=0.015)were associated with carotid intimal thickening and calcification. Conclusion:Carotid artery calcification is prevalent in maintenance peritoneal dialysis patients. Dialysis ages
calcium and phosphorus product
residual renal function are independent risk factors for carotid artery calcification.
关键词
腹膜透析颈动脉钙化颈动脉彩超
Keywords
peritoneal dialysiscarotid artery calcificationcarotid color ultrasonography