Pathological correlation between chronic inflammation and coronary atherosclerosis

Nie Qianyun; Wei Zehong; Deng Guijing; Dong Yuan; Yu Hua; Zou Xing; Li Yongguo; Li Jianbo; Tang Renkuan

doi:10.13406/j.cnki.cyxb.001120

您当前的位置：

首页 >

文章列表页 >

Pathological correlation between chronic inflammation and coronary atherosclerosis

更新时间：2024-01-17

- Pathological correlation between chronic inflammation and coronary atherosclerosis
- Journal of Chongqing Medical University Vol. 41, Issue 12, Pages: 1230-1233(2016)
- 作者机构：
  
  1. 重庆医科大学基础医学院法医学教研室
  2. 重庆市江津区公安局交通巡逻警察支队
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001120
  CLC： R543.3
- Published：2016，
扫描看全文
[1]聂倩云,魏泽红,邓贵菁,董渊,余华,邹星,李永国,李剑波,唐任宽.慢性炎症与冠状动脉粥样硬化的病理学相关性分析[J].重庆医科大学学报,2016,41(12):1230-1233.

Nie Qianyun, Wei Zehong, Deng Guijing, et al. Pathological correlation between chronic inflammation and coronary atherosclerosis. [J]. Journal of Chongqing Medical University 41(12):1230-1233(2016)
[1]聂倩云,魏泽红,邓贵菁,董渊,余华,邹星,李永国,李剑波,唐任宽.慢性炎症与冠状动脉粥样硬化的病理学相关性分析[J].重庆医科大学学报,2016,41(12):1230-1233. DOI： 10.13406/j.cnki.cyxb.001120.

Nie Qianyun, Wei Zehong, Deng Guijing, et al. Pathological correlation between chronic inflammation and coronary atherosclerosis. [J]. Journal of Chongqing Medical University 41(12):1230-1233(2016) DOI： 10.13406/j.cnki.cyxb.001120.

摘要

目的:从病理学角度探讨慢性炎症与冠状动脉粥样硬化（coronary atherosclerosis

CAS）的相关性。方法:回顾性分析涉及慢性炎症性和（或）CAS患者的病历及尸体检验资料。结果:CAS合并一种及以上慢性炎症216例

其中男性159例（73.61%）

女性57例（26.39%）;左冠状动脉前降支最易发生粥样硬化及狭窄;CAS患者中患慢性支气管炎（chronic bronchitis

CB）196例

CB与CAS呈正相关（rs=0.404

P=0.000）

且是CAS发生的危险因素之一（OR=4.852

95%CI=2.898

.124

P=0.000）

其他慢性炎症如慢性肾盂肾炎、慢性胃肠炎、慢性食管炎、慢性淋巴细胞甲状腺炎及慢性宫颈炎与CAS均无明显相关性（P

0.05）。结论:CB是CAS发生发展的危险因素之一;临床上应重视CB的治疗

从而降低冠心病的发生率和死亡率。

Abstract

Objective:To explore correlation between chronic inflammation and coronary atherosclerosis(CAS)according to pathological method. Methods:Medical records and autopsy data of patients with CAS and/or chronic inflammatory diseases were analyzed retrospectively. Results:There were 216 patients with CAS accompanied with mild chronic inflammatory diseases. One hundred and fifty-nine patients were male and 57 patients were female. Left anterior descending branch was the most vulnerable part to atherosclerosis and stenosis. There were 196 patients with chronic bronchitis(CB)in CAS patients. There was a positive correlation between CB and CAS(rs=0.404

P=0.000)

and chronic bronchitis was one of the risk factors of CAS(OR =4.852

95% CI =2.898 to 8.124

P=0.000)

whereas other chronic inflammation

such as chronic pyelonephritis

chronic gastroenteritis

chronic esophagitis

chronic lymphocytic thyroiditis and chronic cervicitis and CAS had no significant correlation with CAS(P >0.05). Conclusion:CB is one of the risk factors for CAS. It is important to treat CB so as to decrease the incidence and mortality of coronary heart disease.

关键词

慢性支气管炎冠状动脉粥样硬化慢性感染危险因素

Keywords

Chronic bronchitiscoronary atherosclerosischronic infectionrisk factors

references

Views

166

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Risk factors of contrast-induced nephropathy in patients with diabetes after percutaneous coronary intervention and its prognosis

Clinical distribution characteristics and analysis on risk factors of extracranial carotid artery stenosis in patients with acute ischemic stroke

Correlation between the cardio-ankle vascular index and cardiovascular risk factors in health examination population

Prevalence and risk factors of impaired fasting glucose among physical examination population in the western new city of Chongqing

Risk factors of neonatal necrotizing enterocolitis and prognostic factors of surgical treatment

Related Author

Zhang Shanwen

Qu Xiaolong

Meng Jing

Hu Houyuan

Li Jing

Tian Ting

Shi Zhenghong

Feng Bin

Related Institution

Department of Cardiology,the First Affiliated Hospital of Third Military Medical University

Department of Neurology,the Second Hospital of Lanzhou University

Department of Cardiovascular Medicine,The First Affiliated Hospital of Chongqing Medical University

Department of Nursing,The First Affiliated Hospital of Chongqing Medical University

Teaching and Research Section of Health Statistics,College of Public Health and Management,Chongqing Medical University

⁰