Survey on periodontal health status of Xinjiang Uygur and Han patients with Alzheimer’s diseases

Reyila·Jureti; Wei Yiru; He Panlong; Shen Yue; Gulinuer·Awuti

doi:10.13406/j.cnki.cyxb.001083

您当前的位置：

首页 >

文章列表页 >

Survey on periodontal health status of Xinjiang Uygur and Han patients with Alzheimer’s diseases

更新时间：2024-01-17

- Survey on periodontal health status of Xinjiang Uygur and Han patients with Alzheimer’s diseases
- Journal of Chongqing Medical University Vol. 41, Issue 12, Pages: 1267-1271(2016)
- 作者机构：
  
  新疆医科大学第一附属医院牙周黏膜科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001083
  CLC： R749.16;R781.4
- Published：2016，
扫描看全文
[1]热依拉·居热提,魏奕茹,何攀龙,沈玥,古丽努尔·阿吾提.新疆汉维两民族阿尔茨海默病患者的牙周健康状况调查[J].重庆医科大学学报,2016,41(12):1267-1271.

Reyila·Jureti, Wei Yiru, He Panlong, et al. Survey on periodontal health status of Xinjiang Uygur and Han patients with Alzheimer’s diseases. [J]. Journal of Chongqing Medical University 41(12):1267-1271(2016)
[1]热依拉·居热提,魏奕茹,何攀龙,沈玥,古丽努尔·阿吾提.新疆汉维两民族阿尔茨海默病患者的牙周健康状况调查[J].重庆医科大学学报,2016,41(12):1267-1271. DOI： 10.13406/j.cnki.cyxb.001083.

Reyila·Jureti, Wei Yiru, He Panlong, et al. Survey on periodontal health status of Xinjiang Uygur and Han patients with Alzheimer’s diseases. [J]. Journal of Chongqing Medical University 41(12):1267-1271(2016) DOI： 10.13406/j.cnki.cyxb.001083.

摘要

目的:了解新疆汉维两民族阿尔茨海默病（Alzheimer’s disease

AD）患者组与认知功能正常组（cognitively normal

ND）的牙周健康状况。方法:选择年龄为50

0岁的被确诊为AD的患者62例（AD组）与认知功能正常者63例（ND组）

对所有纳入对象的牙周状况进行检查和评估。通过AD简易智力状况检查表（mini-mental state examination

MMSE）的测评结果来评估所有调查对象的认知损害程度

根据结果进一步将调查对象分为轻、中、重度。检测调查对象的牙龈指数（gingival index

GI）、菌斑指数（plaque index

PI）、探诊深度（probing depth

PD）、牙周附着水平（clinical attachment level

CAL）和出血指数（percentage of bleeding sites

BOP%）。结果:AD组所有的牙周指数均高于ND组

且随着AD的病程进展

其牙周状况愈发恶化

差异具有统计学意义（P

0.05）。根据认知损害程度分组

每组之间GI、PI、PD、CAL和BOP%均有统计学差异（P

0.05）。新疆汉族AD患者牙周状况和新疆维吾尔族AD患者牙周状况的差异无统计学意义（P

0.05）。结论:牙周健康状况随着AD的病程进展而逐渐恶化

且与个人的认知功能密切相关。

Abstract

Objective:To understand the periodontal health status of Uygur and Han patients with Alzheimer’s diseases(AD). Methods:Totally 62 patients who were diagnosed as AD(AD group)and 63 patients with normal cognitive function(ND group)in the age range of 50 to 80 years old were enrolled and their periodontal status was examined and evaluated. The degree of cognitive impairment was evaluated by Alzheimer’s mini mental state examination table(MMSE)

and subjects were divided into mild

moderate and severe subgroups. The gingival index(GI)

plaque index(PI)

probing depth(PD)

periodontal attachment level(CAL) and bleeding index(BOP%)of the subjects were detected. Results:All the periodontal indexes in AD group were higher than those in ND group

and the periodontal condition became worse with the progression of AD

with statistically significant differences(P<0.05). There were significant statistical differences in GI

CAL and BOP% among subgroups of cognitive impairment(P<0.05). There was no significant statistically difference in periodontal status of Xinjiang Han AD patients and Xinjiang Uygur AD patients(P >0.05).Conclusion:Periodontal health status gradually deteriorates with the progress of the AD

and closely relates with the individual’s cognitive function.

关键词

阿尔茨海默病认知功能障碍慢性牙周炎口腔健康状况

Keywords

Alzheimer’s diseasecognitive dysfunctionchronic periodontitisoral health status

references

Views

108

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Bioinformatics analysis of differentially co-expressed genes in peripheral blood and hippocampal tissue of patients with Alzheimer’s disease

Picroside Ⅱ improves Aβ-induced learning and memory deficits in mice by enhancing autophagy

CX3CL1 improves neuronal function in mice with Alzheimer’s disease by inhibiting microglial pyroptosis

Water extract of Dendrobium nobile Lindl. alleviates learning and memory impairment through synaptic plasticity modulation and glial cell activation in APP/PS1 mice

Gene function analysis of ATRNL1 and ceRNA network construction in Alzheimer’s disease

Related Author

Zhong Yishi

Wu Yinru

Gao Jian

Song Weiqi

Chen Peiliang

Chen Ziting

Wu Xianbo

Li Zhaolun

Related Institution

Department of Epidemiology，School of Public Health，Southern Medical University

Chongqing Institute of Medicinal Plant Cultivation， Chongqing College of Traditional Chinese Medicine

Pediatric Research Institute，National Clinical Research Center for Child Health and Disorders， Ministry of Education Key Laboratory of Child Development and Disorders，Chongqing Key Laboratory of Translational Medical Research in Cognitive Development and Learning and Memory Disorders， Children’s Hospital of Chongqing Medical University

Department of General Medicine，Chengdu Second People’s Hospital

School of Forensic Medicine/Forensic Judicial Appraisal Center，Guizhou Medical University

⁰