Investigation on atherosclerotic cardiovascular disease risk in patients with type 2 diabetes mellitus

Pu Danlan; Yin Jingxia; Tang Ping; Liao Yong; Yang Gangyi

doi:10.13406/j.cnki.cyxb.001067

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Investigation on atherosclerotic cardiovascular disease risk in patients with type 2 diabetes mellitus

更新时间：2024-01-17

- Investigation on atherosclerotic cardiovascular disease risk in patients with type 2 diabetes mellitus
- Journal of Chongqing Medical University Vol. 41, Issue 11, Pages: 1131-1136(2016)
- 作者机构：
  
  1. 重庆医科大学附属第二医院内分泌科
  2. 武警重庆总队医院内分泌科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001067
  CLC： R54;R587.2
- Published：2016，
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[1]蒲丹岚,尹经霞,唐萍,廖涌,杨刚毅.2型糖尿病患者动脉粥样硬化性心血管疾病风险横断面研究[J].重庆医科大学学报,2016,41(11):1131-1136.

Pu Danlan, Yin Jingxia, Tang Ping, et al. Investigation on atherosclerotic cardiovascular disease risk in patients with type 2 diabetes mellitus. [J]. Journal of Chongqing Medical University 41(11):1131-1136(2016)
[1]蒲丹岚,尹经霞,唐萍,廖涌,杨刚毅.2型糖尿病患者动脉粥样硬化性心血管疾病风险横断面研究[J].重庆医科大学学报,2016,41(11):1131-1136. DOI： 10.13406/j.cnki.cyxb.001067.

Pu Danlan, Yin Jingxia, Tang Ping, et al. Investigation on atherosclerotic cardiovascular disease risk in patients with type 2 diabetes mellitus. [J]. Journal of Chongqing Medical University 41(11):1131-1136(2016) DOI： 10.13406/j.cnki.cyxb.001067.

摘要

目的:探讨2型糖尿病（type 2 diabetes mellitus

T2DM）患者动脉粥样硬化性心血管疾病（atherosclerotic cardiovascular disease

ASCVD）高风险（心血管风险可视化评估工具QRISK2≥10%）的现状及相关危险因素。方法:搜集武警重庆总队医院2015年7月至2016年1月25

4岁住院或门诊T2DM患者共271例。按照心血管风险可视化评估工具QRISK2评分检测项目要求

采用统一的调查表

收集被调查人员的社会人口学特征、主要疾病特征以及生化指标

主要包括年龄、性别、吸烟、一级亲属早发（

60岁）心血管疾病史、既往病史、身高、体质量、血压及血脂情况。结果:调查人群中QRISK2≥10%患者比例占82.66%。男性患者平均QRISK2评分较女性患者平均评分高1.14倍[（23.28±8.77）%vs.（20.31±10.01）%

t=-2.364

P=0.019]。QRISK2评分随年龄呈现逐渐增加趋势

男性患者ASCVD高风险较女性患者更显年轻化[（62.43±8.74）岁vs.（67.20±7.45）岁

t=4.367

P=0.000]

。年龄、是否吸烟、SBP、TG及有无糖尿病慢性并发症是影响QRISK2评分≥10%（ASCVD高风险）的影响因素

是否吸烟为最重要影响因素（OR=297.03

95%CI=31.00

845.66

P=0.000）。结论:通过对QRISK2评分对T2DM患者ASCVD风险进行评估

简便、有效。我院T2DM患者ASCVD风险是较高

有必要进行积极管理干预以减少不良结局事件。T2DM患者ASCVD高风险影响因素较多

包括年龄、病程、吸烟等。

Abstract

Objective:To investigate the prevalence of the atherosclerotic cardiovascular disease(ASCVD)risk in type 2 diabetes mellitus(T2DM)in Armed Police Hospital of Chongqing

to provide a well understanding of the high risk(QRISK2 ≥10%)of ASCVD in T2 DM patients and its associated risk factors and to help health providers make right prevention strategies and measures. Methods:The cross-sectional research was conducted to investigate the prevalence of ASCVD risk in all the hospitalized T2 DM patients aged between25-84 years from July 2015 to January 2016 in Armed Police Hospital of Chongqing. According to requirements of QRISK2 test

a unified questionnaire was used to collect investigators demographic characteristics and major disease characteristics

including age

sex

smoking status

angina or heart attack in a 1st degree relative(< 60 years)

height

weight

blood pressure and blood lipid. Results:The proportion of ASCVD risk(QRISK2≥10%)was 82.66%. The average QRISK2 scores in male patients was 1.14 times higher than that in female patients[(23.28±8.77)% vs.(20.31±10.01)%

t=-2.364

P=0.019]. There was a significantly increasing trend of QRISK2 when compared with different ages. Male patients with high ASCVD risk were statistically younger than female patients[(62.43±8.74)years vs.(67.20±7.45)years

t=4.367

P=0.000]. Logistic regression analysis showed that age

smoking

SBP

TG and the chronic diabetes complications were the related factors to high ASCVD risk

and smoking is the most important factor(OR =297.03

95% CI =31.00-2845.66

P =0.000). Conclusion:ASCVD risk assessment of T2 DM patients through QRISK2 score is convenient and effective. The risk of ASCVD in T2 DM patients in our hospital is high

and it is necessary to take effectively management intervention to reduce adverse outcome events. T2 DM patients with high ASCVD risk may associate some factors

including age

course of disease

smoking status

etc.

关键词

2型糖尿病动脉粥样硬化性心血管疾病QRISK2横断面研究

Keywords

type 2 diabetesatherosclerotic cardiovascular diseaseQRISK2cross-sectional investigation

references

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