Relationship between serum neutrophil-lymphocyte ratio and vascular lesions in type 2 diabetes mellitus

Sun Yaqin; Li Sheli; Li Ya

doi:10.13406/j.cnki.cyxb.001022

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Relationship between serum neutrophil-lymphocyte ratio and vascular lesions in type 2 diabetes mellitus

更新时间：2024-01-17

- Relationship between serum neutrophil-lymphocyte ratio and vascular lesions in type 2 diabetes mellitus
- Journal of Chongqing Medical University Vol. 41, Issue 11, Pages: 1147-1149(2016)
- 作者机构：
  
  1. 延安大学附属医院内分泌科
  2. 西安医学院第一附属医院内分泌科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.001022
  CLC： R587.2
- Published：2016，
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[1]孙雅琴,李社莉,李亚.血清中性粒细胞与淋巴细胞比值与2型糖尿病大血管病变的相关性研究[J].重庆医科大学学报,2016,41(11):1147-1149.

Sun Yaqin, Li Sheli, Li Ya. Relationship between serum neutrophil-lymphocyte ratio and vascular lesions in type 2 diabetes mellitus. [J]. Journal of Chongqing Medical University 41(11):1147-1149(2016)
[1]孙雅琴,李社莉,李亚.血清中性粒细胞与淋巴细胞比值与2型糖尿病大血管病变的相关性研究[J].重庆医科大学学报,2016,41(11):1147-1149. DOI： 10.13406/j.cnki.cyxb.001022.

Sun Yaqin, Li Sheli, Li Ya. Relationship between serum neutrophil-lymphocyte ratio and vascular lesions in type 2 diabetes mellitus. [J]. Journal of Chongqing Medical University 41(11):1147-1149(2016) DOI： 10.13406/j.cnki.cyxb.001022.

摘要

目的:探讨2型糖尿病（type 2 diabetes mellitus

T2DM）患者血清中性粒细胞与淋巴细胞比值（serum neutrophil-lymphocyte ratio

NLR）与大血管病变的相关性。方法:将211例T2DM患者分为单纯T2DM（T）组、合并下肢动脉粥样硬化（L）组、合并颈部动脉粥样硬化（C）组、合并下肢动脉兼颈部动脉粥样硬化（LC）组。收集患者的一般临床指标及生化指标。结果:单因素方差分析及LSD多重比较分析显示

L组、C组、LC组的NLR均数均大于T组（P<0.05）;Logistic多元回归分析结果显示

年龄、舒张压、低密度脂蛋白胆固醇、NLR是2型糖尿病大血管病变的危险因素（P<0.05）。结论:NLR与2型糖尿病大血管病变存在相关性。

Abstract

Objective:To explore the association between serum neutrophil-lymphocyte ratio(NLR)and vascular lesions in type 2 diabetes mellitus(T2DM)patients. Methods:A total of 211 T2 DM patients were recruited and divided into four groups:simple T2DM(T)group

complicated with lower extremity arteries atherosclerosis(L)group

complicated with cervical arteries atherosclerosis(C)group

complicated with lower extremity arteries and cervical arteries atherosclerosis(LC) group. The clinical and biochemical data were collected for comparing the difference in NLR among four groups with the method of one way ANOVA and LSD multiple comparisons. Results:The results showed that NLR mean values of L group

C group

LC group were bigger than those of T group(P<0.05).Age

diastolic pressure

low density lipoprotein-cholesterol

NLR were important risk factors for vascular lesions in type 2 diabetes mellitus. Conclusion:NLR level is associated with vascular lesions in type 2 diabetes mellitus.

关键词

中性粒细胞/淋巴细胞糖尿病大血管病变2型糖尿病

Keywords

neutrophils lymphocyte ratiodiabetes vascular lesionstype 2 diabetes mellitus

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Related Institution

Department of Endocrinology，The First People’s Hospital of Yunnan Province/Affiliated Hospital of Kunming University of Science and Technology

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