Lei Yan, Kang Houyong, Hu Guohua, et al. Application of SP/AP area ratio of electrocochleography in the diagnosis of Meniere’s disease. [J]. Journal of Chongqing Medical University 41(6):632-636(2016)
Lei Yan, Kang Houyong, Hu Guohua, et al. Application of SP/AP area ratio of electrocochleography in the diagnosis of Meniere’s disease. [J]. Journal of Chongqing Medical University 41(6):632-636(2016) DOI: 10.13406/j.cnki.cyxb.000981.
Application of SP/AP area ratio of electrocochleography in the diagnosis of Meniere’s disease
Objective:To analyze and compare summating potential(SP)and action potential(AP)in electrocochleogram for diagnosing Meniere’s disease(MD). Methods:All 96 adults(123 ears)were divided into three groups:control group
MD diagnosed group
MD suspected group. Control group was consisted of 56 subjects with normal function of hearing(76 ears were tested);MD diagnosed group was consisted of 25 subjects(29 ears from 21 subjects with single ear and 4 subjects with double ears);MD suspected group was composed of 15 subjects(18 ears from 12 subjects with single ear and 3 subjects with double ears). The SP/AP amplitude ratio and SP/AP area ratio of MD suspected group and MD diagnosed group were compared. Results:The SP/AP amplitude ratio from 95%reference of control group ranged from 0.01 to 0.32
and the positive standard was higher than 0.32;the SP/AP area ratio from 95%reference was 0. 68-1. 82
and the positive standard was higher than 1.82. In MD diagnosed group
the positive rate of the SP/AP amplitude ratio was 14.29%(15 out of 105);the positive rate of SP/AP area ratio was 25.71%(27 out of 105);the positive ratio of SP/AP area ratio was higher than that of amplitude ratio(χ2=6.050
P=0.014). In MD suspected group
the positive rate of SP/AP amplitude ratio was 16.67%(3 out of 18)and the positive rate of SP/AP area ratio was 77.78%(14 out of 18). There were statistical differences between SP/AP area ratio and amplitude ratio(χ2=9.091
P=0.003);the positive ratio of SP/AP area ratio was higher than that of SP/AP amplitude ratio. Conclusion:SP/AP area ratio is superior to SP/AP amplitude ratio in diagnozing MD.
关键词
耳蜗电图梅尼埃病总和电位/动作电位幅度比面积比
Keywords
electrocochleographyMeniere’s diseasesummating potential/action potentialamplitude ratioarea ratio