Comparison of lung dosimetry between supine and sternal horizon positions during X-ray irradiated radical mastectomy radiation therapy

Xie Yue; Huang Luo; Tan Bing; He Yanan; Yang Han; Wang Ying

doi:10.13406/j.cnki.cyxb.000906

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Comparison of lung dosimetry between supine and sternal horizon positions during X-ray irradiated radical mastectomy radiation therapy

更新时间：2024-01-17

- Comparison of lung dosimetry between supine and sternal horizon positions during X-ray irradiated radical mastectomy radiation therapy
- Journal of Chongqing Medical University Vol. 41, Issue 5, Pages: 504-507(2016)
- 作者机构：
  
  重庆市肿瘤研究所放疗科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.000906
  CLC： R737.9;R730.55
- Published：2016，
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[1]谢悦,黄锣,谭兵,何亚男,杨含,王颖.乳腺癌根治术后全X线照射胸壁及锁骨上区平卧位和胸骨水平位的肺剂量学比较[J].重庆医科大学学报,2016,41(05):504-507.

Xie Yue, Huang Luo, Tan Bing, et al. Comparison of lung dosimetry between supine and sternal horizon positions during X-ray irradiated radical mastectomy radiation therapy. [J]. Journal of Chongqing Medical University 41(5):504-507(2016)
[1]谢悦,黄锣,谭兵,何亚男,杨含,王颖.乳腺癌根治术后全X线照射胸壁及锁骨上区平卧位和胸骨水平位的肺剂量学比较[J].重庆医科大学学报,2016,41(05):504-507. DOI： 10.13406/j.cnki.cyxb.000906.

Xie Yue, Huang Luo, Tan Bing, et al. Comparison of lung dosimetry between supine and sternal horizon positions during X-ray irradiated radical mastectomy radiation therapy. [J]. Journal of Chongqing Medical University 41(5):504-507(2016) DOI： 10.13406/j.cnki.cyxb.000906.

摘要

目的:研究2种体位乳腺癌根治术后全X线照射胸壁及锁骨上区的肺剂量学差异

为进一步选择减轻肺放射性损伤的治疗体位提供理论依据。方法:回顾分析2006年1月至2014年12月在我院行乳腺癌术后胸壁及锁骨上区全X线切线野及单前野放射治疗的192例患者资料

其中平卧位92例

胸骨水平位100例

采集2组患者靶区等剂量曲线及肺剂量体积直方图

评价靶区覆盖度及肺剂量分布的差异。结果:平卧位组及胸骨水平位组90%处方剂量完全覆盖计划靶区

均达到放射治疗剂量学要求

靶区均匀指数及适形指数并无统计学差异（P>0.05）;平卧位组及胸骨水平位组患侧肺V20分别为:（29.9±2.5）%和（32.4±3.2）%（P=0.000）

患侧肺V30:（24.8±6.3）%和（26.8±1.9）%（P=0.002）;患侧肺Dm:（16.4±3.0）Gy和（18.1±1.8）Gy（P=0.000）;全肺V20:（14.6±2.1）%和（17.4±2.5）%（P=0.000）

全肺V30:（8.4±1.6）%和（13.9±1.7）%（P=0.000）;全肺Dm:（7.4±0.7）Gy和（8.2±0.7）Gy（P=0.000）

差异均具有统计学意义。结论:乳腺癌根治术后全X线照射胸壁及锁骨上区

2种体位靶区覆盖度无明显差异;平卧位较胸骨水平位有更优的肺剂量分布。

Abstract

Objective:To study the differences of lung dosimetry in chest wall and supraclavicular area under two commonly used radiation positions during all X-ray irradiated radicalmastectomy radiation therapy(RMRT)

and to provide theoretical references for choosing the optimal radiation position with reduced radioactive damage. Methods:Totally 192 patients from January 2006 to December 2014 treated with RMRT on chest wall

supraclavicular and infraclavicular region

were included in the retrospective analysis.Among them

92 patients were in supine position and 100 patients were in sternal horizon position. The coverage of target and dose distribution of lung were evaluated according to the isodose curve and dose volume histograms of two groups. Results:The radiation treatment was successfully completed conducted for all patients. The volume and dose for the supine and sternal horizon positions were as follows:(1)the ipsilateral lungs:V20

(29.9±2.5)% and(32.4±3.2)%(P=0.000); V30

(24.8±6.3)% and(26.8±1.9)%(P=0.002);Dm

(16.4±3.0)Gy and(18.1±1.8)Gy(P=0.000).(2)the whole lung:V20

(14.6±2.1)% and(17.4±2.5)%(P=0.000);V30

(8.49±1.6)% and(13.9±1.7)%(P=0.000);Dm

(7.4±0.7)Gy and(8.2±0.7)Gy(P=0.000). The above results showed a significant difference in the lung dosimetry between the supine position and sternal horizon position. Conclusion:There is no significant difference between the two positions in dose distribution for RMRT. Supine position have significantly better dose distribution for lung than sternal horizon position.

关键词

乳腺癌术后放疗放疗体位剂量学放射性肺损伤

Keywords

breast cancerpostoperative radiotherapyradiotherapy positiondosimetryradiation-induced pulmonary injury

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