Systemic lupus erythematosus-associated collapsing glomerulopathy

Mei Jing; Du Xiaogang

doi:10.13406/j.cnki.cyxb.000865

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Systemic lupus erythematosus-associated collapsing glomerulopathy

更新时间：2024-01-17

- Systemic lupus erythematosus-associated collapsing glomerulopathy
- Journal of Chongqing Medical University Vol. 41, Issue 3, Pages: 318-321(2016)
- 作者机构：
  
  重庆医科大学附属第一医院肾脏内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.000865
  CLC： R593.241;R692.6
- Published：2016，
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[1]梅净,杜晓刚.系统性红斑狼疮相关性塌陷性肾小球病研究进展[J].重庆医科大学学报,2016,41(03):318-321.

Mei Jing, Du Xiaogang. Systemic lupus erythematosus-associated collapsing glomerulopathy. [J]. Journal of Chongqing Medical University 41(3):318-321(2016)
[1]梅净,杜晓刚.系统性红斑狼疮相关性塌陷性肾小球病研究进展[J].重庆医科大学学报,2016,41(03):318-321. DOI： 10.13406/j.cnki.cyxb.000865.

Mei Jing, Du Xiaogang. Systemic lupus erythematosus-associated collapsing glomerulopathy. [J]. Journal of Chongqing Medical University 41(3):318-321(2016) DOI： 10.13406/j.cnki.cyxb.000865.

摘要

塌陷性肾小球病（collapsing glomerulopathy

CG）最初是在人类免疫缺陷病毒（human immunodeficiency virus

HIV）阳性患者中发现的一种特别的肾脏病

现在认为它与许多其他的疾病相关

比如系统性红斑狼疮（systemic lupus erythematosus

SLE）。SLE相关性CG（SLE-associated CG）是指在SLE患者中发现的一种罕见的临床病理实体

并除外其他引起CG的主要因素（比如HIV、细胞病毒B19、丙肝病毒、药物等）

临床上以大量蛋白尿

对免疫抑制剂治疗反应差和急进性肾功能恶化为特点。本文对近年来国外有关SLE相关性CG的研究进展进行综述。

Abstract

Collapsing glomerulopathy(CG)

once known as a special renal disease in human immunodeficiency virus(HIV)-positive patients

has since been recognized in association with numerous other conditions

such as systemic lupus erythematosus(SLE). SLEassociated CG is a distinct clinicopathologic entity in patients with SLE who are not associated with HIV

parvovirus B19

hepatitis C virus

drugs or the primary causes of CG

and is characterized by significant proteinuria

poor response to immunosuppressive therapy

and rapid progression to renal failure. In this article

we review recent progress on SLE-associated CG.

关键词

塌陷性肾小球病系统性红斑狼疮

Keywords

collapsing glomerulopathysystemic lupus erythematosus

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Related Institution

Department of Radiology,The First Affiliated Hospital of Xi’an Jiaotong University

Shaanxi Engineering Research Center of Computational Imaging and Medical Intelligence

Shandong University

Department of Clinical Laboratory, College of Clinical Medicine, Chongqing Medical University

重庆医科大学临床学院肾内科

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