Objective:To investigate the influencing factors of re-stenosis in cerebral atherosclerosis patients with symptomatic middle cerebral artery stenosis after stenting. Methods:The clinical data of 145 patients with symptomatic middle cerebral artery(MCA)

stenosis underwent stenting were analyzed retrospectively.The restenosis rate after stenting was followed-up with transcranial Doppler(TCD)and digital subtraction angiography(DSA). Follow-up examination was performed on 121 patients with stenting and then all patients were divided into artery stenosis and normoal groups. The length of MCA stenosis

type of stent

risk factors and their correlations with restenosis were analyzed. The significant differences of the restenosis rate with and without related risk factors were examined by chi-square test. Results:There were 196 stenosis among the 145 patients

and 164 stents were placed in these patients. The mean stenosis rate of the MCAs before the procedure was(82.3±7.9)%

and immediately after the procedure was(31.6±4.9)%. Twentysix patients(26/121

21.49%)had re-stenosis of less than 50%. Univariate analysis showed that there was no correlation between lesion length

age

sex

drinking

coronary heart diseases and restenosis rate. Logistic regression analysis showed that the correlation among type of stent

smoking

diabetes

hypertension and stent restenosis was statistically significant;they were independent risk factors.Conclusion:Re-stenosis in cerebral atherosclerosis patients with symptomatic middle cerebral artery stenosis after stenting is correlated with stent types

smoking and diabetes. Controlling hypertension

diabetes mellitus and avoiding excessive smoking can reduce the risk of restenosis after operation.